Taking grape seed extract with breakfast may reduce certain stress markers in people with metabolic syndrome according to a new study from the University of California, Davis. The research is noted in the American Botanical Council's HerbClip.
Metabolic syndrome is a cluster of conditions that occur together and increase your risk of heart disease, stroke and diabetes. They include: increased blood pressure, high blood sugar level, excess body fat around the waist and abnormal cholesterol levels. More than one in five Americans has metabolic syndrome, according to the Cleveland Clinic, who reports the condition affects more than 40 percent of people in their 60s and 70s.
In a single-center, randomized, crossover, 2-arm, placebo-controlled study, University of California researchers analyzed the effect of 300 mg of grape seed extract on a dozen people, mean age of 45, who had at least three factors of metabolic syndrome. They were given the supplement an hour before eating a high carbohydrate, high fat meal. The release did not indicate whether that meal was IHOP's new Jelly Donut Pancake Breakfast, which is available with a side of bacon. If they had, they might have attracted more than 12 participants.
According to HerbClip, the authors of the study conclude that: “grape seed extract enhanced the postprandial antioxidant capacity of plasma, suppressed the increases in OxLDL, and reduced postprandial glucose concentrations as compared to placebo in patients with metabolic syndrome.“ This is good news.
Researchers did not know “whether these changes would also occur following lunch or dinner since the grape seed extract was only consumed acutely before breakfast.” Because of that, they couldn't extrapolate whether or not the extract would have a long term effect. The study provided “helpful preliminary research on the effect of grape seed extract on postprandial antioxidant/glucose/insulin balance in patients with metabolic syndrome,” according to HerbClip.
This is only the most recent research suggesting the benefits of grape seed extract. Another study suggested that the compound reduces plaque formation and resulting cognitive impairment in an animal model of Alzheimer's disease. That study appeared in The Journal of Neuroscience.
For detailed information on the state of the polyphenol business, from grape seed to curcumin and more, check out the Nutrition Business Journal / Engredea monograph report: polyphenols edition.