Cutting-edge research - June 2010

Curcumin cuts cholesterol
Curcumin, the dietary polyphenol isolated from turmeric, has been shown to decrease cholesterol levels. Its mechanism of action had been thought to be related to increased expression of LDL receptors. However, this new study elucidates that curcumin actually works by inhibiting cholesterol uptake in intestinal enterocytes by inhibiting the expression of NPC1L1, the key transporter of cholesterol in the cell membrane.
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DSM's resVida resveratrol helps the heart
Data from two analyses of the first human study of resVida brand trans-resveratrol, from DSM, showed cardiovascular health benefits in humans. The research was presented at the 4th International Conference on Polyphenols and Health in Yorkshire, England, Dec 7-10, 2009. ResVida almost doubled the flow-mediated dilation of the brachial artery, which is an important indicator of a healthy cardiovascular system.
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Biothera's Wellmune WGP reduces respiratory infections
The body of research demonstrating that Wellmune WGP® can reduce upper respiratory tract infection symptoms and improve the psychological well-being of individuals with stressful lifestyles continued to grow with the presentation of new data at Experimental Biology 2010. In a study of 122 healthy men and women, participants taking 250mg Wellmune WGP daily for 12 weeks reported a statistically significant 58 per cent reduction in upper respiratory tract infection symptoms, compared with individuals taking a placebo. Participants also rated their overall well-being and vigour at about 10 per cent higher than the placebo group.
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Not all veggies are created equal
Americans get most of their beta-carotene from carrots. But sweet potatoes have twice the content. Beta-cryptoxanthin is consumed mostly from oranges and OJ — but papaya has 15 times the amount. Lutein and zeaxanghin is mostly eaten via spinach — but cooked kale has triple the carotenoid content compared to raw spinach. Fully 14 phytonutrients were assayed and compared, in research unveiled at the Experimental Biology conference.
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