BRADENTON, FL – Annie Eng, president of HP Ingredients, has announced that her company has signed an exclusive distribution agreement with Shawn Talbott of GLH Nutrition and Supplement Watch Inc. (www.supplementwatch.com) to handle sales and marketing of Citricoma™, a new patent-pending blend of Citrus PMF (polymethoxylated flavones) and Eurycoma longifolia, for the healthy weight loss/management market.
Talbott, the developer of Cortislim, which racked up $200 million in sales in its first 12 months, holds four patent applications covering his “next generation” Citricoma™, and has conducted a clinical trial on its efficacy in weight loss, energy, and mood.
The 12-week study of 29 moderately overweight men and women followed a moderate calorie-restricted diet based on resting metabolic rate, plus a moderate exercise program (five days a week including aerobic and strength training), stress management techniques and the supplement.
“Most diet programs might help you to shed a few pounds quickly, but as soon as you resume your normal eating habits, you gain all the weight back. These diet programs continue to fail because they typically restrict the type of food the dieter can eat, are often unbalanced and do not provide the body with the proper nutrients. Moreover, such restricted diets are very hard to maintain over a long period of time,” explains Talbott. “In this study, all the subjects were moderately overweight as judged by their BMI and were already exercising and watching their diets. Our program actually encouraged them to exercise less and eat more. When we added the Citricoma™ supplement, they continued to lose weight throughout the 12-week period, showed significantly lower cholesterol levels, especially LDL, and experienced better mood and higher energy levels.”
Polymethoxylated flavones (PMFs), particularly tangeretin, and nobilitin, represent a class of “super flavonoids” extracted from citrus peels that exhibit approximately three-fold potency in their ability to reduce cholesterol levels as compared to other citrus flavonoids. 11(beta)-HSD1 is an enzyme that is responsible for the modulation of cellular cortisol exposure and plays an important role in healthy weight, blood glucose, and cholesterol management. Talbott’s patent applications disclose the inhibition of 11(beta)-HSD1 with PMFs to reduce systemic and local cortisol concentrations (liver and adipose tissue), and promoting healthy blood sugar control, healthy cholesterol level, and weight management.
Higher levels of cortisol, a primary stress hormone, have been correlated with increased appetite and weight gain. Stress, such as following a weight loss program, can put the body into a catabolic state, in which the body can experience muscle loss, reduced metabolic rate with corresponding reduced calorie expenditure and lower perceived energy levels, and weight gain in the form of fat. Eurycoma longifolia, standardized to 22% eurypeptides has been shown in a human clinical study to enhance lean body weight and sustained energy by promoting a favorable ratio of cortisol to testosterone. “Researchers believe that controlling the cortisol and testosterone levels helps prevent the body from increasing fat storage and increases a person’s baseline energy,” Eng says.
She adds that Citricoma™ has tremendous potential for several markets: weight management, cholesterol management, anti-aging, fitness and sports nutrition, and energy.
In tandem, Eng announced that HP Ingredients is funding the second study, a double-blind, placebo-controlled human clinical trial involving 50 subjects, of Citricoma™ and weight loss, which should be completed by March.
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