This vitamin-like ingredient from Kyowa Hakko has been known to function as a precursor of phospholipid and acetylcholine synthesis, and also to enhance the release of neurotransmitters such as norepinephrine. In a study published last year in the International Journal of Eating Disorders, Cognizin was found to have potential for reducing cravings and increasing feelings of satiety. After six weeks of supplementation, researchers mapped participants' brains and found that three areas relevant to appetite control and behavioral inhibition – the lateral orbitofrontal cortex, the insular cortex and the amygdalaIn – had the greatest activation in high-dose participants, and those participants consequently saw the greatest decline in appetite for high-
Fabuless, used in dairy applications, is a patented combination of palm and oat oils that are formulated in an emulsion and shown to reduce calorie intake at subsequent meals. The slow digestion of the oat oil allows Fabuless to penetrate to the intestines, causing the body to identify a relatively high level of undigested fat. This in turn suppresses hunger and promotes satiety.
From Chemi Nutra, this patented compound is a phosphobioflavonic complex of N-oleoyl-phosphatidyl-ethanolamine (NOPE), which contains oleoyl ethanolamine (OEA) bound to phosphatidylethanolamine (PE), a naturally occurring phospholipid found in many foods, and green tea extract epigallocatechin gallate (EGCG). OEA binds to a cell receptor class in the intestine, and then signals the brain to cut appetite.
Pharmachem's Phase 1 Hunger Controller
This flavored beverage powder contains Olibra, a clinically studied ingredient for appetite control and satiety. Phase 1 has been shown to reduce appetite by as much as 20 percent. Pharmachem also offers Phase 2 Carb Controller and Phase 3 Sugar Controller as part of its weight-loss ingredient portfolio.
P.L. Thomas' Satiereal
Satiereal is derived from the flowers of saffron crocus, Crocus sativus L. Until now saffron has been a prohibitively expensive ingredient. But Satiereal is made from a crocus cultivar rich in active saffron constituents, so it is cost effective as a weight-loss formula. Satiereal's clinically proven formula boosts serotonin, increasing satiety while cutting appetite. In a trial, 100 percent of female participants reported decreased hunger while taking Satiereal.
Gencor Pacific Group's ingredient Slimaluna is the only scientifically validated appetite suppressant ingredient to combine fat reduction and appetite suppression, according to the company. In a clinical study, participants reported statistically significant hunger reduction, as well as loss of waist circumference and fat loss when using Slimaluna. The ingredient has been used in beverages, capsules, tablets, chocolate, meal replacements and baking applications.