New research reveals how NEM works

New research reveals how NEM works

New published research provides additional insights into the mechanism of action for ESM Technologies' NEM brand eggshell membrane ingredient for joint health. 

Stratum Nutrition announces newly published support for NEM®, manufactured by partner ESM Technologies, evaluating the effects of various manufacturing methods for eggshell membrane products. Researchers at ESM Technologies feel this new information provides additional insights into the mechanism of action for their NEM brand eggshell membrane ingredient for joint health. 

In collaboration with the Jordan Valley Innovation Center within Missouri State University, the scientists evaluated three different hydrolyzates of eggshell membrane (fermentation, enzymatic, or chemical) in cell cultures of two different types of human immune cells. All three hydrolyzates were found to activate the gene transcription factor NF-kB, although the chemical hydrolyzate was about 10-fold less effective versus the fermentation and enzymatic hydrolyzates. NF-kB plays a fundamental role in the functioning of the immune system and occurs very early in the inflammatory cascade.

“It’s always rewarding to gain insight into the observed efficacy of one of our ingredients through fundamental research, particularly when this leads to the potential for new intellectual property,” commented Dr. Kevin J. Ruff, director of scientific and regulatory affairs for ESM Technologies, the manufacturer of NEM. The results of these studies were published in the February issue of the Journal of Inflammation Research.

This study, along with additional published studies, show further substantiation for NEM supporting a healthy inflammatory response. For more information on this new published data, please contact Dr. Kevin Ruff at [email protected]

 

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