Gencor is pleased to introduce its new ingredient, ActivAMP. The ingredient is extracted from Gynostemma pentaphyllum, an adaptogenic herb, and activates an enzyme called AMP-activated protein kinase (AMPk).
A 12-week randomized, double-blind, placebo-controlled study on 80 overweight participants investigated the effects of ActivAMP (then called Actiponin) on body weight, fat loss and other metabolic markers. The results showed statistically significant decreases in the active group compared to placebo group in body fat mass, percent body fat, body weight and BMI, and total abdominal fat area. An eight-week study on mice showed that oral administration of ActivAMP resulted in decreased body weight gain and liver weight with AMPk activation in the soleus muscle, and a phytochemical study of ActivAMP revealed that the extract contains two novel dammarane-type saponins (damulin A and damulin B) that strongly activated AMPk in cultured L6 myotube cells.
“AMPk is often called the ‘master metabolic regulator’ and switches on the same fat-burning and energy-producing metabolic processes that exercise does,” said Dr. Paul Clayton, chief scientific advisor, Gencor. “Human, animal and phytochemical studies have demonstrated the effect of ActivAMP in supporting the metabolic process through AMPk activation.”
ActivAMP is available as a free-flowing powder and is suitable for use in powders, tablets and capsules. Gynostemma pentaphyllum has been used traditionally in teas for centuries. For more information, visit Gencor's booth, number 613, at the Engredea trade show in Anaheim, March 7 to 9.