New Water-Soluble Cinnamon Extract Expands Applications

Cactus Botanics announced its launch of water-soluble cinnamon extract that preserves its naturally occurring polymeric polyphenols.

Cinnamon extract has been more widely studied for its applications in promoting a healthy insulin response by mimicking the action of insulin-induced signaling via its receptor; and is a featured ingredient in numerous supplements for this market. More recently, says Carol Chew, General Manager of Cactus Botanics, a compelling study has looked at the role of an aqueous extract of cinnamon in promoting protection against carcinogenesis.

According to the 2005 study appearing in Cancer Letters, hyperinsulinemia has long been associated with obesity and diabetes, and there is now increased speculation as to its role in the development of cancer. This particular study explored possible anti-cancer properties of water-soluble, polymeric polyphenols from cinnamon on three myeloid cell lines (Jurkat, Wurzburg, and U937). The study authors stated that they have “demonstrated that a water-soluble fraction, high in polymeric polyphenols from cinnamon, reduced cellular growth in a dose-dependent manner in both a lymphoma and two leukemic cell lines. Sensitivity of growth to the extract was similar among the cell lines. The decrease in proliferation of the tumor cells observed with CE is in agreement with growth arrest that is typically seen when cultured cells are treated with polyphenolic compounds, such as curcumin, tea catechins and genistein.” 1

“This study is important for developers of dietary supplements and functional foods because it adds a layer of confidence to consumers concerned about maintaining health and decreasing their susceptibility to major illness,” says Cheow. “Our water-soluble cinnamon extract is versatile and produced in pharmaceutical-grade facilities for superior quality and safety.”

1. Schoene, NW, et al. “Water-soluble polymeric polyphenols from cinnamon inhibit proliferation and alter cell cycle distribution patterns of hematologic tumor cell lines” Cancer Letters 230 (2005) 134–140.

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