A study published in the current issue of the Annals of Neurosciences journal featuring KSM-66 Ashwagandha demonstrated significant increase in lifespan, both in absolute terms and relative to alternative ashwagandha extracts or to a placebo. The study concludes that KSM-66 Ashwagandha can help improve longevity in healthy persons. An important finding from the study is that the KSM-66 full spectrum extract has a significantly stronger effect than hydro-alcoholic extracts of ashwagandha.
Like the vast majority of lifespan extension studies in the modern scientific literature, this study is an animal study. This research used Caenorhabditis Elegans worms because their metabolic processes are similar to those of humans. The animal species were provided by the U.S. Federal Government's National Institutes of Health, Bethesda, Maryland.
The study had a large sample size of over three hundred individual organisms. The researchers studied lifespan of the organisms as affected by treatment with a placebo, with the KSM-66 full-spectrum ashwagandha extract and with a normal hydro-alcoholic extract of ashwagandha. For each individual organism, the time to end-of-life was carefully measured using modern assay and examination techniques. Statistical survival analysis was then conducted. Individuals treated with the KSM-66 full-spectrum ashwagandha extract lived, on an average, 21% longer than individuals treated with the placebo and 14% longer than individuals treated with the hydro-alcoholic extract of ashwagandha. These results suggest that while hydro-alcoholic extracts of ashwagandha can improve lifespan significantly, the KSM-66 full-spectrum ashwagandha extract is even more effective.
The study was conducted by professors at the prestigious Indian Institute of Technology Kanpur, frequently cited as one of the top three science research universities of Asia.