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From The September 2000 Issue of Nutrition Science News

Cell-life Extender Linked to Cancer

London—Previously publicized as a virtual "fountain of youth" for cells, it now appears the enzyme telomerase may also promote cancer. Because of its ability to extend the life of human cells—allowing them to divide indefinitely—telomerase was considered as a potential treatment for conditions such as diabetes and liver disease. However, in a recent study conducted by David Beach of University College London, when a gene that stimulates telomerase production was inserted into breast cancer cells, it was discovered that a gene called "c-myc," which has been linked to a wide variety of cancers, was also activated. Although the treated breast cells were not determined to be cancerous, they seemed to be moving in that direction.

Researchers believe the prolonged cell life was the catalyst behind the c-myc stimulation rather than telomerase itself; however, they suggest that more research needs to be done before telomerase can be used safely.



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