Major Factors Thought To Be Involved in Increased Intestinal Permeability Associated With Irritable Bowel Disease

• Alcohol use
• Cancer radiation therapy
• Excessive simple sugar consumption
• Excessive stress
• Fasting
• Food allergens
• Gastrointestinal infections
• NSAID use
• Nutrient insufficiencies
• Premature birth
• Whole food exposure prior to 4-6 months of age