Anti-aging: Keeping pep in your step

Anti-aging: Keeping pep in your step

Consumers want and expect to remain healthy and active longer. Here are some ingredients that help can help achieve that goal.

Check out the chart of participants at any of the big citizen-class endurance events around the country, whether it’s the New York marathon, a cycling event in the Rocky Mountains or your local sprint triathlon, and you’ll see they have something in common:  The average age of participants is creeping up.

 Some of that can be attributed to demographics, of course (there are more of us codgers out there) but a lot of it is because people’s expectations are changing.   They don’t expect to become infirm after age 50, as many in the Greatest Generation did.

Helping an aging consumer maintain optimum health has a lot of upsides.  Many of these people are motivated, and want to maintain general health and mobility so that they can remain physically active for as long as possible (the level of exercise is one of the best predictors for good overall health as one ages).  And many have (or at least had) higher average disposable incomes and household net worth than the median consumer.

 Helping someone stay healthy could include all of the ingredients in this issue.  But for the purposes of this analysis, the products break down into two main subcategories:  those that support cognitive health and those that support cellular health and longevity.


Supporting cognitive health

One of the biggest fears associated with aging in the United States is the risk of developing Alzheimer’s disease. An estimated 5.4 million Americans suffered from Alzheimer’s in 2011, according to the Alzheimer’s Association.  All but 200,000 of those were over the age of 65.  For a 65-year-old, the current lifetime risk for developing Alzheimer’s is about 1 in 10 for men and close to 1 in 5 for women.

So it’s no wonder products with a cognitive-health support claim are a hot property.  One of those that’s supported with a strong science dossier is Cognizin, a branded citicoline product from Kyowa Hakko.  A recent conducted study at the University of Utah showed subjects showed a statistically significant increased focus and attention over a six-week period. One of Cognizin several methods of activity is to support cellular integrity, which makes it an important ingredient to consider for an anti-aging cognitive product, according Karen Todd, director of marketing for Kyowa Hakko.  Other longtime players in the anti-aging cognitive support realm are oils, whether marine or algal, that deliver DHA.


Keeping cells healthy

All systems in the body, from the brain on down, rely on the integrity of the cells that make up the tissues.  Keeping those cells intact, functioning well and replicating themselves reliably is the key to aging gracefully.  Here’s where antioxidants shine, even if their marketing claims have lost some luster.  And the master of the antioxidant universe is glutathione.

“From an anti-aging standpoint, it’s important to keep your glutathione level up.  It’s the master antioxidant; everything focuses around glutathione,” said Todd, whose employer, Kyowa Hakko, markets a branded form of glutathione called Setria.

The longtime rule of this category has been resveratrol, the antioxidant derived from red wine and the foundation of the French Paradox. ResVida from DSM shines here with a solid science backing of its “nature-identical” resveratrol molecule.

Another recent antioxidant addition is pterostilbene, an antioxidant said to have a bioavailability advantage over resveratrol.  Pterostilbene is also present in red wine and is found in blueberries and other fruits.  “Oxidative stress is a hallmark of aging. Anything that’s able to show a positive effect in reducing levels of oxidative stress in the body is going to be a good ingredient for the anti-aging category,” said Jeremy Bartos, Ph.D., the ingredient manger for pTeroPure, which makes the eponymous synthetic version of pterostilbene, an antioxidant compound found in blueberries and other fruits.

Other recent additions to this category include full-spectrum tea extracts such as Teafense from Stratum Nutrition and Assuritea from Kemin Industries.

Condition Specific Directory




Algatechnologies, Ltd.

AstaPure natural astaxanthin


BioCell Technology, LLC

BioCell Collagen II

Patented dietary ingredient substantiated by multiple clinical trials for joint and skin benefits. Containing highly bioavailable hydrolyzed collagen, low molecular weight (MW) hyaluronic acid and chondroitin sulphate, it provides a multi-layered support for healthy joint and counteracts both natural and photo-aging processes in the skin.  


BioCell Collagen II CG-WS

Cosmetic-grade, water-soluble, topical formulation of BioCell Collagen II. Collagen-derived peptides and low MW HA are provided to enhance skin beauty via supplying both building blocks of skin structure and bioactive molecules that inhibits hyaluronidase. Dermatologist-reviewed and hypoallergenic.



Freeze-dried powder of [begin ital[Wasabia japonica[end ital]. It is rich in isothiocyanates (ITC) which induce Nrf2, a master switch for cytoprotective enzymes, providing antioxidant, liver-detoxifying, and Cox2-specific anti-inflammatory properties. This novel nutraceutical is the most potent [begin ital]Wasabia japonica[end ital] available, containing 15,000 ppm ITC.

[email protected]


Newport Beach, California


Biotropics Malaysia


Clinically researched and shown to support overall health, energy, muscle strength, muscle mass and enhance masculine vitality. PHYSTA™ uses a patented water extraction and freeze-dried technology developed in collaboration with the Massachusetts Institute of Technology (MIT) to deliver the purest and efficacious form of [BEGIN ITAL]Tongkat Ali.[END ITAL]

[email protected]

+60 3 2245 8000

Kuala Lumpur, Malaysia


BI Nutraceuticals



Bioenergy Life Science, Inc.

Bioenergy Ribose

Bioenergy Ribose naturally raises depleted energy levels due to aging. Decreased mitochondrial function can leave individuals feeling tired and fatigued from daily activity.  Bioenergy Ribose increases energy naturally and effectively to help people feel better.

[email protected]


Minneapolis, Minnesota, USA


Cyvex Nutrition


A highly refined omega-3 oil available in bulk and softgels that features a 1:1 ratio of EPA and DHA, and also provides a rich source of DPA fatty acid. OmegaActiv is truly vertically integrated and traceable as Cyvex maintains complete control over the source, menhaden, which is certified sustainable by FOS.

[email protected]


Irvine, California, USA


Draco Natural Products

Anti-Aging TCM Extract Formulas


Kyowa Hakko USA



Lallemand Health Ingredients

Lalmin Vita D – A natural source of vitamin D


Maypro Industries




Dragon’s Blood


Nutraceuticals International

LycheeBerri™  Litchi chinensis 10%

A great source of vitamin C and potassium. It also contains phosphorus, calcium, magnesium, and protein. Applications: tablets, desserts, capsules, ice cream, soft drinks, jams, smoothies, wine.

[email protected]


Elmwood Park, New Jersey, USA



pTeroPure Pterostilbene

Pterostilbene, a compound found in blueberries an other fruits, is closely related to resveratol.  It is  a potent antioxidant known to support cognitive function, health wellness and longevity, and has shown to have a higher bioactivity potential than resveratrol.





Soft Gel Technologies, Inc.

EZ Mega 3 Softgels

An extremely stable and deodorized fish-oil concentrate in an easy-to-swallow softgel that is neutral in taste and contaminant free. The highest standards were used to manufacture this fish-oil concentrate, so that it is not only free of potential toxins, but it is also odorless and minimizes aftertaste and reflux.

[email protected]

800-360-7431 or 323-726-0700

Los Angeles, California, USA


Stratum Nutrition



Telos Ceuticals, LLC



UAS Laboratories, Inc.


A unique formulation that combines the benefits of proven DDS® Probiotics containing Lactobacillus acidophilus (DDS®-1), Bifidobacterium longum, Bifidobacterium bifidum, Bifidobacterium lactis and FOS and high quality Parry Organic Spirulina.  Blend 006 helps maintain digestive health, healthy immune function and a healthy balance of intestinal flora.  Spirulina  helps contribute to healthy aging.

[email protected]


Eden Prairie, Minnesota, USA





XSTO Solutions, LLC


Carno-Life® from Hamari Chemicals is a Pharmaceutical grade preparation of L-Carnosine. As a dipeptide of beta-alanine and histidine, Carnosine has long been studied for its anti-aging benefits. By reducing molecular cross-linking, binding with potentially harmful carbonyl groups and contributing significant anti-oxidant benefits, Carno-Life® should be considered for all anti-aging formulations.

[email protected]


Morristown New Jersey, USA

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