Joint health is often grouped with bone health, but the two couldn’t be more different. It would be like grouping eye health with brain health because, after all, they are both so close to one another! We are here to inform you that joint health is an entirely different construct, with utterly different ingredients and mechanisms of action from bone health. The difference is as clear as that between glycosaminoglycans and osteocalcin. Got it? Herewith, the 4-1-1 on joint health.
Fi: What are your projections for the growth of the sector for the coming year?
Heather Thompson, Global Marketing & Communications Manager, Stratum Nutrition
Discomfort in the joints is an ongoing issue due to age, activity, weight, and other factors, so I feel this will always be a growing category. Consumers continue to look for more natural ways to continue daily life activities more comfortably. Worldwide estimates are that 9.6 percent of men and 18 percent of women aged over 60 years have symptomatic osteoarthritis. Eighty percent of those with osteoarthritis will have limitations in movement, and 25 percent cannot perform their major daily activities of life. These numbers continue to rise as the world population becomes more overweight and sedentary. And since participation in sports and other active endeavors is often sporadic, stress and injury to joints is an inevitable consequence. Therefore in the coming year the supplements industry should experience a steady gain in the joint health sector, with a continued interest in new joint health products that are easy to take on a regular basis and that provide measurable benefits to the end consumer.
Paul Dijkstra, CEO, InterHealth Nutraceuticals
The joint health category is constantly growing and introducing new products/ingredients. Innovation continues to be a strong driver in both the dietary supplement and food and beverage industries. It seems the future market is ready for innovation with new ingredients and products that are clinically proven to work and that are safe. Manufacturers want new ingredients that allow them to differentiate their products in the marketplace and re-invigorate the entire category.
Fi: Is the overall aging population a good thing for suppliers of joint health ingredients?
HT: Yes, an aging population is certainly a significant contributing factor to the growing need for joint health solutions. Increasingly more, people desire to be active into middle age and beyond. Ease of movement and joint comfort are integral to an active, healthy lifestyle. But the 21st century senior citizen isn’t just content with being active. These individuals are vibrant and busy in all aspects of their lives. Therefore they desire a supplement regimen that is simple, convenient and easy to maintain.
PD: Joint health is a popular issue among aging Baby Boomers. InterHealth is seeing increased interest in UC-II for joint-health supplements that target the active Boomer—aging cyclists, marathon runners, triathletes, basketball players even the weekend warrior.
Fi: How does your ingredient fit into the overall joint health picture?
HT: NEM is a complete, natural joint health solution comprised of an inherent matrix of glycosaminoglycans including glucosamine, chondroitin, dermatan and keratan sulfate, and hyaluronic acid. NEM also contains collagen and other beneficial proteins and sulfur-containing amino acids.
NEM is an egg-derived ingredient, shown in clinical trials to support joint comfort and flexibility within 7-10 days. Its small 500 mg effective dose allows for greater formulation flexibility and an easy, once-a-day complete joint health solution.
PD: UC-II is a patented, clinically studied ingredient sourced and manufactured in the United States for joint health. UC-II is manufactured in a GMP-certified facility. UC-II is GRAS and is an FDA-notified and published new dietary ingredient (NDI) that supports joint comfort, mobility and flexibility. Having NDI status as well as GRAS status is definitely a key marketing and sales driver for InterHealth.
A big advantage of UC-II is that the dosage is only 40 mg a day. This fact is a distinct benefit for many consumers, especially older individuals who may have difficulty taking larger pills. With compliance being a big factor for efficacy as well as repeat sales, it is important to make the regimen as convenient as possible for consumers. Furthermore, a product that combines UC-II with other joint health ingredients will still result in a manageable supplement size. Manufacturers who choose to formulate with UC-II will not only be able to take advantage of the small 40 mg dosage, but will benefit from the published peer-reviewed research demonstrating that UC-II is twice as effective as glucosamine and chondroitin.
Condition Specific Directory: JOINT HEALTH
Superba Krill Oil
In Superba Krill Oil, the phospholipid omega-3s EPA and DHA and are highly enriched with phosphatidylcholine, essential to proper cell membrane structure and integrity in all living things. Recent human clinical studies have shown that phospholipid omega-3 provide more benefits than triglyceride omega-3s.
AK Biotech Co.
Omega-3 fatty acids
African Bush Products Inc.
CalKon provides the joint health benefit of chondroitin without sodium and provides a boost of calcium to support healthy bones. Chondroitin sulfate is an important component of cartilage that provides resistance to compression. Consumers enjoy the benefits of chondroitin but don’t need the added sodium that is often included.
City of Industry, California
Anderson Global Group LLC
Pharmaceutical-grade Osamine glucosamine is the premier shellfish-based glucosamine available in the marketplace. No other glucosamine source comes close to meeting the quality and efficacy of this premium material. Osamine originates from wild shrimp and is manufactured in a state-of- the-art pharmaceutical facility ensuring unrivaled purity and quality.
BioCell Technology LLC
BioCell Collagen is a naturally occurring matrix of hydrolyzed collagen type II, low molecular weight hyaluronic acid and chondroitin sulfate. This patented ingredient, substantiated by human clinical trials, is differentiated by comprehensive support for both collagen and glycosaminoglycans, and by biological properties, including remarkable bioavailability and chondrocyte stimulation for potential cartilage regeneration.
EstraFlex is a proprietary blend of cetylated fatty acids, including cetyl myristate, cetyl myristoleate, cetyl oleate, cetyl palmitoleate and cetyl palmitate. Cetyl myristoleate has been shown to help manage various joint discomforts and to improve the flexibility and range of motion of the joint.
Newport Beach, California
Bioastin Hawaiian Astaxanthin
Fortigel (bioactive collagen peptides)
Indena USA Inc.
Meriva Bioavailable Curcumin
Meriva is a patented delivery form of curcumin utilizing Indena's proprietary PHYTOSOME technology. Pharmacokinetic comparison studies have shown Meriva to improve bioavailability of curcuminoids by nearly 30-fold. Meriva is supported by three clinical studies related to joint health.
InterHealth Nutraceuticals Inc.
InterHealth’s UC-II is twice as effective as glucosamine + chondroitin at just 40 mg a day. UC-II fits perfectly in combination products or works as a small, once-a-day, joint-health option. Filed NDI, GRAS and sourced and made in the United States – make the switch to UC-II.
National Enzyme Co.
Serrazimes, a proteolytic system
Neptune Technologies and Bioressources
NKO phospholipids-bounded omega 3s and antioxidants
Nutra Bridge Corp
Pharmachem Laboratories Inc.
Celadrin is a natural ingredient for joint health composed of a proprietary blend of special fatty acids. It has been shown in multiple studies to reduce pain and improve mobility in people suffering from a variety of joint, muscle and tendon-related ailments. A study published in the Journal of Rheumatology found that Celadrin, taken orally, provided an improvement in knee range of motion and overall function over placebo.
Kearny, New Jersey
Curcumin C3 Complex
Pre-clinical and clinical studies of curcumin and its derivative curcuminoids are increasing, as evidence emerges of curcumin's potential in preventive and intervention therapy for joint health.
East Windsor, New Jersey
Soft Gel Technologies Inc.
Perluxan softgels contain a patented, proprietary hops resin extract standardized to contain a high dosage of alpha acids, and have been clinically tested for fast-acting relief of minor aches and pains.
NEM is a Natural Eggshell Membrane ingredient that supports joint comfort and flexibility within 7-10 days. Multiple clinical studies have shown the small, 500 mg dose to be fast and effective. NEM is composed of naturally occurring glycosaminoglycans and key proteins like collagen which are essential for healthy joints. NEM is 100% domestically sourced and self-affirmed GRAS.
TSI Health Sciences Inc.
PUREFLEX glucosamine and chondroitin
UAS Joint Formula with glucosamine, chondroitin, MSM and boswellia seratta
Univestin joint care ingredient
Vitaco Health (NZ) Ltd.
Biolane Active Green Lipped Mussel Extract