BENICIA, Calif. – July 9, 2008 –Super CitriMax®, InterHealth Nutraceuticals’ patented calcium/potassium (-)hydroxycitric acid weight management ingredient, was shown to have no toxic effects in a two-generation reproduction study. The results, published in the June issue of Toxicology Mechanisms and Methods, further affirms the long-term safety of the popular diet ingredient.
The study evaluated the effects of Super CitriMax® on the reproductive systems of male and female rats, specifically the post-natal maturation and reproductive capacity of their offspring, and possible cumulative effects through multiple generations. Animals’ diets were supplemented with varying doses of Super CitriMax® equivalent to 1018 and 1524 mg/kg body weight a day in male and female rats, respectively.
Both parents and offspring were examined daily and a variety of reproductive parameters were assessed. Upon conclusion of the study, the reproductive systems and performance of animals receiving Super CitriMax® were no different than those of healthy controls. Parameters evaluated included sexual maturity, fertility and mating, gestation, giving birth, litter properties, lactation and development of offspring.
In a subsequent next-generation, follow-up study, offspring of the first study were given up to 1524 mg per kg of body weight of Super CitriMax®. There was no evidence of maternal or fetal toxicity in their offspring as well.
“This study is the latest in a massive body of research that confirms the broad spectrum safety of Super CitriMax®,” stated CEO Paul Dijkstra. “Super CitriMax® has undergone more than two decades of safety and efficacy research at some of the nation’s most prestigious universities with more than 20 studies published in peer-reviewed journals. All research demonstrates that it is both efficacious and safe.”
In view of comprehensive safety findings, Super CitriMax® has been affirmed GRAS (Generally Recognized As Safe). The ingredient is heat stable and highly soluble; it is also tasteless, odorless and colorless in solution, making it an excellent choice for inclusion in a wide variety of functional foods, beverages and snacks. Many manufacturers, including beverage powerhouses, have incorporated Super CitriMax® into their functional beverages, including Sobe® Lean from PepsiCo.
With regard to efficacy, comprehensive research, including human clinical studies, consistently demonstrate that Super CitriMax® is highly effective in reducing excess weight and maintaining healthy body weight. Super CitriMax® burns fat, suppresses appetite and inhibits fat production, without stimulating the central nervous system. It has also been shown to modulate serotonin and neuropeptide Y levels (regulators of appetite control), and promote normal cholesterol levels.
About InterHealth Nutraceuticals, Inc.
InterHealth Nutraceuticals researches, develops, markets and distributes specialty nutritional ingredients, which are sold worldwide to manufacturers of dietary supplements and nutraceutical food and beverage products. The company’s products include Super CitriMax®, ChromeMate®, Aller-7®, OptiBerry®, UC-II®, L-OptiZinc®, Protykin® and ZMA®. For more information about InterHealth and its products, call 1-800-783-4636 or 1-707-751-2800 (outside U.S.) or visit the website at www.interhealthusa.com.
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