Article highlights cardiovascular benefits of Mediterranean diet

Article highlights cardiovascular benefits of Mediterranean diet

Joseph L. Evans Ph.D., Manager, Pharmacology for Stratum Nutrition and Novus authored an article that highlights promising nutrients present in the Mediterranean diet have been shown in clinical trials to reduce oxidized low-density lipoprotein (OxLDL).


Joseph L. Evans, Ph.D., Manager, Pharmacology for Stratum Nutrition and Novus research fellow recently authored "Cardiovascular Health Benefits of the Mediterranean Diet.Targeting oxidized LDL," which was published in the March/April 2011 issue of the Agro FOOD INDUSTRY Hi-tech journal, a leading peer-reviewed European journal providing in-depth coverage of developments in the functional food and nutraceutical markets. The article highlights some promising nutrients present in the Mediterranean diet that have been shown in clinical trials to reduce oxidized low-density lipoprotein (OxLDL), a pro-atherogenic mediator and biomarker for cardiovascular disease.

"There are several historically-used measurements for identifying individuals at risk for developing cardiovascular disease, including levels of LDL- and HDL-cholesterol, total cholesterol, and high blood pressure to name a few," noted Dr. Evans. "However, there are other biomarkers, including OxLDL and the OxLDL / HDL cholesterol ratio that have been shown in clinical research to be more sensitive indicators for discriminating between individuals with and without coronary artery disease when compared to the commonly measured biomarkers. And consuming a Mediterranean diet is an effective way to reduce levels of OxLDL and improve overall cardiovascular health."

Currently, the American Heart Association estimates that nearly 81 million Americans (1 in 3 adults) have one or more types of cardiovascular disease and oxidative stress and inflammation are well- known contributors to heart health issues. The traditional

Mediterranean diet is rich in foods with strong antioxidant properties, such as fruits, vegetables, olive oil and nuts. Research has indicated that the nutrients contained in these foods increase the expression of those genes involved in our body's antioxidant defense system, and suppress those genes involved in advancing inflammation and atherogenesis. While the precise mechanism(s) responsible for nutrient-mediated reduction in OxLDL is unknown, it likely involves the increased expression of circulating and intracellular antioxidant enzymes, along with the inhibition of enzymes that contribute to increased production of reactive oxygen species.

About Stratum Nutrition

Stratum Nutrition is a Novus International business Empowering Product Innovation through science supported specialty and functional ingredients for manufacturers and marketers of foods, beverages and dietary supplements. Stratum leverages the Novus core competencies in nutritional research and innovation as well as the corporate commitment to protecting the environment by considering economic, environmental and social factors to ensure that our ingredients offer safe, efficient and sustainable health solutions.

Stratum offers a portfolio of branded, value-added ingredients that are progressive, safe and reliable. These ingredients are based on consumer need, supported by science and the backing of a trusted multi- national company. For more information on Stratum Nutrition, please visit www.StratumNutrition.com.

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