“"Omega-3 (also known as n-3) fatty acids are considered to have cardiovascular health benefits. One way to determine a health benefit is to combine and review data from several high-quality, published clinical studies in a so-called meta-analysis, which establishes criteria that individual studies must meet. The product of this systematic review found the health impact of consumption of greater than one-quarter gram per day of omega-3 long-chain fatty acids to be associated with a 35 percent reduction in the risk of sudden cardiac death. Further risk reductions were observed from reviewing Japanese data indicating that intakes of about a gram or more per day may offer protection against non-fatal heart attacks. The researchers included individuals from AHPA member company Cantox, the Global Organization for EPA and DHA Omega-3s (GOED), Denomega Nutritional Oils, Ocean Nutrition Canada, and Monsanto."
From the British Journal of Nutrition, October 2011:
The objective of the present study was to determine whether the consumption of ≥ 250 v. < 250 mg of the long-chain n-3 fatty acids (n-3 LCFA) per d is associated with a reduction in the risk of fatal and non-fatal CHD in individuals with no prior history of CHD. A comprehensive and systematic review of the published scientific literature resulted in the identification of eight prospective studies (seven cohorts and one nested case-control study) that met predefined inclusion criteria. Relative to the consumption of < 250 mg n-3 LCFA per d, the consumption of ≥ 250 mg/d was associated with a significant 35.1 % reduction in the risk of sudden cardiac death and a near-significant 16.6 % reduction in the risk of total fatal coronary events, while the risk of non-fatal myocardial infarction was not significantly reduced. In several meta-analyses, which were based on US studies, risk of CHD death was found to be dose-dependently reduced by the n-3 LCFA, with further risk reductions observed with intakes in excess of 250 mg/d. Prospective observational and intervention data from Japan, where intake of fish is very high, suggest that n-3 LCFA intakes of 900 to 1000 mg/d and greater may confer protection against non-fatal myocardial infarction. Thus, the intake of 250 mg n-3 LCFA per d may, indeed, be a minimum target to be achieved by the general population for the promotion of cardiovascular health.
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