Cactus Botanics On Fucoidan and Alginates extracted from Laminaria Japonica

Laminaria japonica has a long history of use in Asia, including Japan, China, South Korea and other countries. It has been used as a traditional Chinese herbal medicine and possesses many physiological functions for human health and skin care.

Since the middle of the 1990’s, there have been several scientific studies which have exposed the secrets regarding Laminaria japonica efficacy. Fucoidan and Alginates are believed to be the key factors.

Fucoidan, a class of natural sulfated heteropolysaccharides, isolated from the brown algae Laminaria japonica, is known to contain not only L-fucose residues as the main sugar constituent, but also galactose, mannose, xylose, glucuronic acid and so on.

Some observations from selected studies include:

Fucoidan is a sugar-based sulfated polysaccharide that retains moisture and has immunostimulating, anticoagulating, and antiaging activity.6-9
Two separate French studies published in Biomedical Pharmacotherapy show that fucose and fucose-rich polysaccharides penetrate the skin, decrease free radical scavenging, and increase the cell proliferation to slow down the aging of skin cells.10,11
In France, woman have traditionally use Fucoidan to increase hair growth and soften rough and damaged skin.12
It is been shown to be effective in breast cancer prevention.15

Cactus Botanics introduced Fucoidan in Aug 2005. After two years, it has perfected the production process of its Fucoidan products and has now enlarged the specifications.

Brown Seaweed Extract (Alginates 50%)

Brown Seaweed Extract (Fucoidan 20%)

Brown Seaweed Extract (Fucoidan 35%)

Brown Seaweed Extract (Fucoidan 85%)

Some main players in the Food Supplements and Pharmaceutical industries have already brought materials from Cactus Botanics to perform clinical tests for pharmaceutical purpose, or to make Food Supplements.

As Fucoidan and Alginates are water-soluble sulfated polysaccharides, they have also attracted Cosmetic companies’ attention. They are used in skin care cream and facial mask for anti-wrinkle purposes and to retain moisture.

Cactus Botanics’ Fucoidan targets the Food Supplement and cosmetic markets and we look forward to more partners with this product. For more information, please contact: [email protected]


References:

1. Environment & Resource Technology Ltd. "Economic Appraisal
of Seaweed," circa 1995: Comhairle nan Eilean Siar.
www.w-isles.gov.uk/minch/seaweed/seaweed-04.htm
2. Natalia and Varinia Michalum, Skin Care and Cosmetic Ingredients
Dictionary, 2nd ed. (Albany, NY: Milady, Thomson Learning, 2001), 73.
3. Nagwa E. Awad, "Biologically active steroid from the green alga
Ulva lactuca," Phytother Res 14 (2000): 641-43.
4. Isao Kubo et al. "Antibacterial activity of crinitol and its potentiation." Nat Products 55 (1992): 780-85.
5. Tsutomu Fujimura et al. "Treatment of human skin with an extract
of Fucus vesiculosus changes its thickness and mechanical properties," J Cosmet Sci 53 (2002): 1-9.
6. TA Kuznetsova et al. "Immunostimulating and anticoagulating activity of fucoidan from brown algae," Antibiot Khimioter 48 (2003): 11-13.
7. O Berteau et al. "Characterization of a new alpha-L-fucosidase isolated from the marine mollusk Pecten maximus that catalyzes the hydrolysis of alpha-L-fucose from algal fucoidan (Ascophyllum nodosum)," Glycobiology 12 (2002): 273-82.
8. I Fodil-Bourahla et al. "Effect of L-fucose and fucose-rich oligo-and polysaccharides (FROP-s) on skin aging: penetration, skin tissue production and fibrillogenesis," Biomed Pharmacother 57 (2003): 209-15.
9. G Peterszegi et al. "Studies on skin aging. Preparation and properties of fucose-rich oligo-and polysaccharides. Effect on fibroblast proliferation and survival," Biomed Pharmacother 57 (2003): 187-94.
10. I Fodil-Bourahla et al. "Effect of L-fucose and fucose-rich oligo-and polysaccharides (FROP-s) on skin aging: penetration, skin tissue production and fibrillogenesis," Biomed Pharmacother 57 (2003): 209-15.
11. G Peterszegi et al. "Studies on skin aging. Preparation and properties of fucose-rich oligo and polysaccharides. Effect on fibroblast proliferation and survival," Biomed Pharmacother 57 (2003): 187-94.
12. "IMPAG: Active Algae Ingredients: Out of the Biosphere Reserve
into Cosmetics," IMPAG News 12 (2002): www.impag.de.
13. ET Miller, Salon Ovations: Day Spa Techniques. (Albany, NY: Milady Publishing, 1996).
14. MS Matsui et al. "Sulfated polysaccharides from red microalgae have anti-inflammatory properties in vitro and in vivo," Appl Biochem Biotechnol 104 (2003): 13-22.
15. Anticancer Res 1996 May-Jun;16(3A):1213-8 The dietary intake of Laminaria, a brown seaweed, and breast cancer prevention. Teas J.

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