A team of experts from Swinburne University of Technology, Hawthorn, Australia reviewed the randomized, controlled clinical trials to evaluate the cognitive effects of Bacopa monnieri Linn. and published a systematic review in the Journal of Alternative and Complementary Medicine (Vol 18, No 7, 2012). Out of total 64 clinical trials reviewed, only six studies met the inclusion criteria and two studies were on BacoMind®, manufactured by Natural Remedies, Bangalore, India.
The trials were analyzed for methodologic quality using a purpose-designed modified Jadad scale of total 10 points. Here, one point was given when each of the following criteria was satisfied, with higher scores reflecting superior methodologic quality: (I) Was the study randomized? (II) Was randomization detailed and appropriate? (III) Was the study double-blinded? (IV) Was the blinding detailed and appropriate? (V) Was there a control group? (VI) Was the control described in detail and appropriate? (VII) Were the exclusion criteria adequate? (VIII) Was the dosage used in a therapeutic level? (IX) Were withdrawals and dropouts described? and (X) Were the data reported clearly and adequately?
The Systematic review included two of the clinical studies on BacoMind viz 1) Morgan and Stevens (2010) titled “Does Bacopa monnieri improve memory performance in older persons? results of randomized, placebo-controlled double-blind trial” and, 2) Barbhiya et al., (2008) titled “Efficacy and tolerability of BacoMind on memory improvement in elderly participants - A double blind placebo controlled study”, have scored highest on the Jadad scale for quality amongst the studies included.
BacoMind is a clinically proven (both in elderly and children) standardized phytochemical composition derived from the plant Bacopa monnieri Linn, and is launched after an extensive research work by Natural Remedies, Bangalore. BacoMind has scientific backup of multiple in vitro, animal and clinical studies to substantiate its beneficial effects for cognition. Further, this systematic review adds value by revealing the quality of the studies conducted on BacoMind for cognitive enhancement. Visit bacomind.com for more on BacoMind.