Evidence-based products

Study Claim: Consumption of resistant starch benefits digestive health.

Published: Moreau NM, Martin LJ, et al. Restoration of the integrity of rat caeco-colonic mucosa by resistant starch, but not by fructo-oligosaccharides, in dextran sulfate sodium-induced experimental colitis. Br J Nutr 2003 Jul; 90(1):75-85.

Abstract: Using dextran sulfate sodium to induce ulcerative colitis, the study analysed how the choice of dietary fibre high amylose resistant starch (RS) and fructo-oligosaccharide (FOS) affected caeco-colonic inflammation and the healing process. Seventy two male rates were divided into groups: control (without dietary fibre), FOS diet and RS diet, with each category containing rats with and without induced colitis. After seven and 14 days, the caeco-colonic inflammatory injuries were observed using caecal and faecal samples analysed for products of fermentation short-chain fatty acids such as butyrate, acetate and propionate.

Initial signs of mucosal healing in the colitis-induced rats appeared on day seven and continued throughout the experiment for the RS group; healing did not occur in the FOS group. It was thus concluded that increased levels of butyrate in the caecum of RS-fed rats compared with FOS and control diets prove that resistant starch can enhance both colonic fermentation and improve recovery from colitis, with implied benefits for other diseases related to short-chain fatty acid production and poor microflora balance such as irritable bowel syndrome, and inflammatory bowel diseases including Crohn?s disease, ulcerative colitis and colorectal cancer.

Potential Applications: National Starch Food Innovation?s high amylose resistant starch used in the study is sold as an ingredient for food formulations under the brand names Novelose and Hi-maize.

More info: Tel: +44 161 925 4700 www.foodinnovation.com
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