Fenchem study finds natural vitamin E shows more bioavailability

Fenchem study finds natural vitamin E shows more bioavailability

Fenchem completed a study cooperated with a famous university, which suggests that TocoVet(405E), a source of natural vitamin E, more effectively raises serum vitamin E levels in horse when compared to synthetic vitamin E.

Vitamin E is an important antioxidant that keeps free radicals from forming and potentially weakening cells and tissues.

Vitamin E varies in its potency, based on whether it is natural or synthetic. Natural vitamin E is recognized as d-α-tocopherol, or its acetate form, d-α-tocopheryl acetate and is made up of a single isomer. Synthetic vitamin E, termed dl-α-tocopherol, also commonly known as dl-α-tocopheryl acetate contains a mixture of eight different isomers. Of these eight, only one is molecularly equivalent to natural vitamin E.

Fenchem′s TocoVet® (405E), d-α-tocopheryl acetate (feed grade), is white free-flowing powder from natural source. This product is only used Non-GMO IP certified natural vitamin E as raw materials, and produced in utilizing our micro-encapsulated technology, which increasing the absorption of vitamin E.

Fenchem just completed a study cooperated with a famous university, which indicated that TocoVet® raise the horse serum levels more effectively when compared to the synthetic. The study involved 10 Thoroughbred geldings (age 10.75 ± 2.2 years), which were divided randomly into two groups and administered 5000-IU doses of vitamin E. One group was fed with synthetic vitamin E (dl-α-tocopheryl acetate), and the other was fed with TocoVet® (405E) (d-α-tocopheryl acetate). Blood serum samples were collected before dosing and at 3, 6, 9, 12, 24 and 48 hours post-dosing.

Serum vitamin E levels were measured using high-performance liquid chromatography, and relative bioavailabilities were calculated from comparisons of magnitudes of responses measured by areas under the concentration versus time curves (AUC).

The results suggest that TocoVet® (405E), a source of natural vitamin E, more effectively raises serum vitamin E levels in horse when compared to synthetic vitamin E. The relative bioavailability of TocoVet® (405E) is as much as 1.95 times of the synthetic vitamin E.

As a feed additive, Fenchem TocoVet® (405E) can improve Immune system health, antioxidant protection and reproduction of animals. It has a greater bioavailability for horse nutrition. A regular schedule of training and competition makes performance horses susceptible to muscle damage, which is due largely to oxidative stress. TocoVet® (405E) provides vitamin E in a form that is easily absorbed, and is appropriate for horses of all ages that are stabled due to training schedules, travel, or injury.

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