Food Manufacturers Profit from Foods Enhanced with a Tomato Lycopene Health Benefit

Food Manufacturers Profit from Foods Enhanced with a Tomato Lycopene Health Benefit
LycoRed provides food manufacturers with a new road to added profits. Health conscious consumers are increasingly placing foods touting the health benefits of tomato lycopene into their shopping carts. Breads, soy meats, cereals, dairy products and confections all can improve nutrition with super-antioxidant lycopene and complementary tomato phytonutrients. LycoRed launched its new LycoMato® in powder form at this year's IFT Expo in Las Vegas. LycoMato® Powder is specifically suited for fortification and coloring of food products.

Foods displayed at this summer's IFT included Light Life meat analogs - colored with LycoMato® Powder, Elite chocolate bars, French Meadow tortillas and Kashi Heart to HeartTM cereal - fortified with LycoMato® Powder, and Hunts tomato sauces with LycoFibersTM added for viscosity control.

The Functions of Tomato Lycopene and its Role in Human Health
Levy J., Sharoni Y., The Functions of Tomato Lycopene and its Role in Human Health, Herbalgram 62:46-56 (2004)

This comprehensive review article takes a close look at the way lycopene functions in the human body, the mechanism of action, its synergistic relationship with the other micronutrients found in tomato and its role in helping to prevent degenerative diseases. The article highlights the importance, from both a health benefit and safety perspective, of including lycopene in the diet together with the other phytonutrients found naturally in the tomato. Click here to read the full, beautifully illustrated, article.

New Insight into How Lycopene May Help Reduce Prostate Cancer
Ulrich S., Luca B., Volker S., et al, Lycopene and Vitamin E Interfere with Autocrine/paracrine Loops in the Dunning Prostate Cancer Model, Journal of the American College of Nutrition, Vol. 23, No. 1, 34-42 (2004)

New findings suggest that lycopene and vitamin E contribute to the reduction of prostate cancer by interfering with internal autocrine or paracrine loops of sex steroid hormone and growth factor activation/synthesis and signaling in the prostate. Click here to read the abstract.

Tomato Products Most Effective Against Sporadic Prostate Cancer
Wu K., Erdman Jr. J., Schwartz S., et al., Plasma and Dietary Carotenoids, and the Risk of Prostate Cancer a Nested Case-Control Study, American Journal of Epidemiology, 159:32-41 (2004)

The association between plasma carotenoids and prostate cancer risk was investigated in a case-control study nested within the prospective Health Professionals Follow-up Study. Researchers found a statistically significant inverse association between higher plasma lycopene concentrations and lower risk of prostate cancer, which was restricted to older participants and those without a family history of prostate cancer. This observation suggests that tomato products may exhibit more potent protection against sporadic prostate cancer rather than those with a stronger familial or hereditary component. Click here to read the abstract.

Low Lycopene Concentration Associated with Increased Mortality from Certain Cancers.
Mayne S. Cartmel B., Lin H., et al., Low Plasma Lycopene Concentration is Associated with Increased Mortality in a Cohort of Patients with Prior Oral, Pharynx or Larynx Cancers, Cancer Epidemiology Biomarkers & Prevention Vol. 13, 340-345 (March 2004)

In an analysis of beta-carotene, alpha-carotene, lycopene, lutein/zeaxanthin, total carotenoids, retinol, and alpha-tocopherol, only plasma lycopene was significantly inversely associated with total mortality in the full study population of patients being treated for oral cavity, pharynx or larynx cancers. Click here to read the abstract.

Lycopene and B-carotene Responsible for the Effect of Tomato Products on Antioxidant Status
Tyssandier V., Feillet-Coudray C., Caris-Veyrat C., et al, Effect of Tomato Product Consumption on the Plasma Status of Antioxidant Micro-constituents and on the Plasma Total Antioxidant Capacity in Healthy Subjects, International Journal of Epidemiology, Volume 33, Number 3, pp. 518-525 (2004)

This study aimed to identify the plasma antioxidant micro-constituents mainly affected by tomato product consumption, to check whether tomato product consumption can affect antioxidant status, and to identify tomato-product antioxidant micro-constituents mainly involved in the effect of these products on oxidative stress. Researchers found that tomato product consumption can affect not only the lycopene status, but also that of other antioxidant micro-constituents (ß-carotene and lutein). Lycopene, but also ß-carotene, are apparently the main tomato micro-constituents responsible for the effect of tomato products on antioxidant status. Click here to read the abstract.

Tomato Lycopene Well Tolerated in Pharmacokinetic and Toxicity Study
Gustin D., Rodvold K., Sosman J., et al., Single-Dose Pharmacokinetic Study of Lycopene Delivered in a Well-Defined Food-Based Lycopene Delivery System (Tomato Paste-Oil Mixture) in Healthy Adult Male Subjects, Journal of Nutrition 134:1862-1866 (August 2004)

This report details the findings of a single-dose Phase I pharmacokinetic and toxicity study of a food-based formulation of lycopene in healthy adult male subjects. Five dosing groups (n = 5 per group) were sequentially treated with increasing doses of lycopene ranging from 10 to 120 mg. The formulation was well tolerated with minimal side effects, which were mainly of gastrointestinal nature and of very low grade. Click here to read the abstract.

In the News
LycoRed partners with the H.J. Heinz Company, the Morningstar Company and the Prostate Cancer Foundation in petitioning FDA for approval of a qualified health claim indicating the association between consumption of lycopene in tomato products and a reduced risk of prostate cancer. A response from FDA is anticipated early in 2005. Approval from FDA would enable food and dietary supplement manufacturers to make this label claim on products containing LycoMato® and other tomato lycopene products.

Marketing Partnership News
A new look for LycoMato®: LycoRed unveils new logo
After much brainstorming and flowing of creative juices, LycoRed launches its new label-friendly LycoMato® logo. The LycoMato® logo may be licensed for use on products containing LycoMato® oleoresin or powder. For more information on licensing, contact Lorri Danzig.

Print Partnering Program a Success for LycoRed Partners
Companies prominently featuring the LycoMato® logo on their label are eligible to take part in LycoRed's print partnering program. As part of our ongoing effort to help our customers promote their LycoMato® product, LycoRed features LycoMato® products in 1/3 vertical ads in widely distributed consumer magazines alongside full page LycoMato® ads. To see if your product qualifies for free advertising, contact: Scott Larkin

Highlights of the IFT EXPO 2004
LycoRed was a big hit at IFT Expo 2004, with a technical presentation by Dr. Zohar Nir, an exciting big screen TV give-away and a delicious sampling of foods fortified with LycoMato® Powder.

The LycoRed tasting table featured soft tortilla rollups with 3 mg tomato lycopene /34 gram serving, cheese spread with 3 mg tomato lycopene / 4 oz serving, fruit smoothies with 3mg tomato lycopene / 8 oz serving, candy bars, and crackers.

LycoRed tomato products for the food industry are being used for lycopene fortification, natural red coloring and to improve viscosity of sauces and dressings. For more information on LycoRed products developed for the food and beverage industry, contact: Dave Thomas.

LycoMato® The Worldwide Regulatory Picture

    United States
  • self-affirmed GRAS
  • allowable ingredient in dietary supplements and foods
  • color additive petition under review in the U.S.
  • USP monograph draft is under review
  • allowable as a natural food colorant in the LycoMato® powder form
  • functional claim dossier: prevention of DNA damages
  • functional claim dossier: protection from cell damage
  • approved food colorant and for food fortification
  • approved food colorant
  • novel foods application in progress to obtain food use approval
  • LycoMato® powder: allowable for use in foods
  • approved for food fortification
    United Kingdom
  • LycoMato® oleoresin: approved for use in dietary supplements, novel foods application in progress to obtain food use approval
  • LycoMato® powder: allowable for use in foods

Upcoming Events
September 29 - Oct 1 2004
Supply Side West Las Vegas NV
Visit LycoRed at Booth # 1613

Upcoming Media Coverage
Alternative Medicine Digest (national magazine circ. 315,000) November
First for Women (national magazine circ. 1,604,363)

For more studies on LycoMato® go to:

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