Lipid Nutrition Study of Safflorin(tm) Confirms Positive Impact on the Human Immune System

New Clinical Study Using Safflorin (Isomerized Safflower Oil) Has a Significant Effect on Reducing Sore Throats Due to Colds

Channahon, Ill., April 13, 2004 - Lipid Nutrition, a global leader in lipid-based health ingredients, announces that its fourth double-blind, placebo-controlled clinical trial utilizing Safflorin(tm) at the University of Virginia showed that it had a significant positive effect on reducing the incidence of sore throats due to colds.

Forty-five volunteers were subjected with a rhinovirus used for the controlled infection. The volunteers who took Safflorin clearly benefited in that they experienced an overall reduction of symptoms, as well as a reduced incidence of sore throat infection, one of the most uncomfortable symptoms of a common cold infection. The results of the University of Virginia study will be presented for the first time at the 17th International Conference on AntiViral Research in Tucson, Arizona, May 2-6, 2004.

Prior to this clinical study, in May 2003, Lipid Nutrition's first human study at TNO (Netherlands Organization for Applied Scientific Research) published in the European Journal of Clinical Nutrition in 2003 showed that supplementation with Safflorin increased antibody production in healthy people, suggesting that the isomerized safflower oil product could boost the immune system and prevent allergic response in people[1]. Additionally, in 2003, Lipid Nutrition presented to the AOCS (American Oil Chemists Society) additional data from its study in Scotland showing that Safflorin boosts the human immune system by stimulating healthy antibodies and inhibiting allergy related antibodies.

"The first study at TNO provided evidence that Safflorin improves antibody production in humans," said Katinka Abbenbroek, Marketing Director for Lipid Nutrition. "What is exciting about this new human study performed at the University of Virginia is that it investigates Safflorin against experimentally induced illness in humans. The volunteers taking Safflorin experienced an overall reduction of symptoms such as sore throat, sneezing, coughing, and headaches."

Safflorin(tm) is derived from safflower oil by a proprietary process that provides the best balance of the active isomers. Since the active isomer t10,c-12 is the mosteffective for supporting the immune system, Safflorin(tm) contains a 40:60 ratio of the c-9,t-11 and t-10,c-12 isomers. The beneficial effects of Safflorin(tm) have been demonstrated at a supplemental dose of 2 grams daily. It is ideal for use in capsules.

Lipid Nutrition, a division of Loders Croklaan is a global leader in the supply of scientifically sound lipid ingredients from natural origin, which improve and maintain health and well-being. The company offers a variety of branded products, including Clarinol(tm) for body weight management, Marinol(tm) concentrated fish oils for heart health and brain development, Membranol(tm) phosphatidyl choline enriched lecithin for liver health and memory improvement and Betapol(tm) human milk fat substitute for infant nutrition.



[1]R Albers, RPJ van der Wielen, EJ Brink, HFJ Hendriks, VN Dorovska-Taran and ICM Mohede, Effects of cis-9, trans-11 and trans-10, cis-12 CLA isomers on immune function in healthy men, European Journal of Clinical Nutrition (2003) 57, 595-603

The statements made herein have not been evaluated by the U.S. Food and Drug Administration (U.S. FDA). These products are not intended to diagnose, treat, cure or prevent any disease.

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