Company News

LycoRed wins prestigious award for advertising
LycoRed Natural Products Industries, Ltd, was recently presented with the prestigious Ad * Q Award for Outstanding Advertising in recognition of the advertisement that achieved outstanding readership response as measured against all other ads appearing in Nutraceuticals World Magazine, June 2004. The award-winning ad was produced for LycoRed Natural Products in the USA by the fine team at Karlen Williams Graybill Advertising, NY, NY.

Ad*Q awards are presented by Harvey Research, Inc., an independent market research firm. Harvey research measured the number of Nutraceuticals World readers who recalled seeing and reading the ad and the number of readers with buying influence in the product category who recalled seeing and reading it. Using a composite benchmark rating of these statistics they established the overall effectiveness of the ad. The Harvey study provides an objective means of judging advertising effectiveness based on the physical components of the ad as well as its overall strategic approach.

Movin’ on up
Congratulations to Zohar Nir PhD, on his promotion to Global Vice President and to Scott Larkin on his promotion to Vice President of Sales and Marketing – Dietary Supplement Division.

Kashi® takes tomato extract to heart
Kashi® a leader in promoting health and wellness through all-natural foods, has expanded its Heart to Heart® product line to offer instant oatmeal and frozen waffles. Heart to Heart® frozen waffles and Heart to Heart? instant oatmeal join Heart to Heart® ready-to-eat cereal in providing the antioxidant benefits of lycopene from tomato extract (equal to the amount in a medium size tomato per serving) along with an array of healthy ingredients to help reduce cholesterol, support healthy arteries, and manage hypertension. Kashi®products are available nationwide at grocery and natural food stores.

On the International Front
Kagome introduces new yogurt fortified with lycopene
The Japanese diet contains little in the way of tomato products and therefore the average Japanese is likely not getting all the lycopene they need to provide optimum benefits to their health. Kagome Ltd., the largest tomato processor in Japan and the Pacific Rim, has introduced yogurt fortified with natural tomato lycopene. This unique new yogurt product is sweetened with rose hips and is expected to be another big hit for Kagome.


The Role of Lycopene in Preventing DNA Damages
The scientific community is increasingly focusing their interest on the role played by lycopene in preventing DNA damages due to oxidative stress. Damage to DNA is a leading causative factor in the onset of many degenerative diseases. Identification of a dietary ingredient that can help to prevent these damages has important implications for our future healthcare. Below, find two recently published studies on the DNA protective effects of tomato extract and lycopene.

LycoMato® results in decreased levels of DNA damage
As is the case with most studies in which subjects received tomato oleoresin/extract, the material used in the following study was LycoRed’s LycoMato® in soft gelatin capsules.

Karlis Briviba, Sabine E. Kulling, Jutta Möseneder, Bernhard Watzl, Gerhard Rechkemmer, Achim Bub, Effects of supplementing a low-carotenoid diet with a tomato extract for 2 weeks on endogenous levels of DNA single strand breaks and immune functions in healthy nonsmokers and smokers, International Journal of Epidemiology, Volume 33, Number 3, pp. 518-525, August 2004.

This double blind, randomized, placebo-controlled study, involved 15 non-smokers and 12 smokers. It was performed to investigate whether consumption of a tomato oleoresin extract for 2 weeks can affect endogenous levels of DNA single strand breaks in peripheral blood lymphocytes in healthy nonsmokers and smokers.

Intervention with tomato oleoresin extract resulted in significant increases in total plasma lycopene and resulted in decreased levels of DNA strand breaks of about 32% in nonsmokers and 39% in smokers. Treatment with the tomato extract had no effect on lymphocyte proliferation, NK cell activity, IL-2 production and TNFa production, but it significantly reduced IL-4 production in smokers. Placebo supplementation of nonsmokers and smokers for 2 weeks did not significantly affect lycopene plasma levels or DNA damage in either group. Click here to read the abstract.

Lycopene may reduce LNCaP human prostate cancer cell survival
Hwang, Effect of lycopene on lipid peroxidation and oxidative DNA damage in LNCaP human prostate cancer cells. Food Science Biotechnology, 2004; 13(3): 297-301.

In this placebo-controlled study conducted at the University of Illinois, Department of Human Nutrition, investigators characterized the antioxidant and prooxidant effects of water solubilized lycopene at different concentrations using a prostate cancer cell line. After 6, 24, and 48 hr incubation, LNCaP cells were harvested and used for each measurement. Cellular proliferation was determined using the MTT colorimetric assay. Lycopene inhibited cell growth in a dose-dependent manner and growth inhibition was 55% at 1 microM after 48 hr incubation. The study found that lycopene can protect mammalian cells against membrane and DNA damage and might play a protective role against tumor promotion.

Visit the LycoNews Archives for more on tomato lycopene and prevention of DNA damage

Tomato lycopene May Spell Relief for Frequent Night-time Risers
Lycopene in combination with other antioxidants may bring relief to men suffering from nocturia and other related symptoms.
Sabine Rohrmann, Ellen Smit, Edward Giovannucci and Elizabeth Platz, Association between serum concentrations of micronutrients and lower urinary tract symptoms in older men in the third National Health and Nutrition Examination Survey, Urology 64: 504-509, 2004

This study aimed to evaluate the association of serum micronutrients with lower urinary tract symptoms. Study subjects included 2497 men, 60 years old and older, who participated in the Third National Health and Nutrition Examination Survey from 1988 to 1994 and for whom serum concentrations of vitamins A, C and E, carotenoids and selenium had been measured previously. The men studied all had three or four of the following symptoms: nocturia, hesitancy, incomplete emptying, and/or weak stream. None had undergone noncancer prostate surgery. Controls were men without symptoms, who had never undergone noncancer prostate surgery. Researchers found that greater circulating concentrations of vitamin E, lycopene and selenium antioxidant micronutrients were inversely associated with LUTS. Click here to read the abstract.

For more studies on LycoMato® go to:

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