Mannatech Assay Published in Distinguished Journal of AOAC INTERNATIONAL

COPPELL, TX, Jul 06, 2005 (MARKET WIRE via COMTEX) -- Mannatech, Incorporated (MTEX) announced today that its first scientific assay on aloe vera, authored by its own Dr. Alexis Eberendu, et al, titled: "The Quantitative Colorimetric Analysis of Aloe Polysaccharides as a Measure of Aloe Vera Quality in Commercial Products," has been published in the June 2005 issue of the Journal of AOAC INTERNATIONAL [Association of Analytical Chemists International], a publication from AOAC INTERNATIONAL which contains fully referenced contribution papers in the field of chemical and biological analysis: which include original research on new techniques and applications, collaborative studies, authentic data of composition, studies leading to method development, meeting symposia, newly adopted AOAC approved methods and invited reviews.

Richard Ko, Co-Chair of the AOAC's Methods Committee on Dietary Supplements, stated that "Mannatech has developed a method to identify and control the quality of commercial products containing aloe extracts... the aloe vera manufacturing industry has been troubled by the perception that many products on the market are misbranded or contain poor quality extract. Mannatech expressed a need for a good, validated analytical method to control this expanding market. Dr. Eberendu volunteered to make his method available for publication and to conduct the necessary validation studies under AOAC's guidance... Plans are underway to validate the method. This is a prime example of an industry initiative, where the AOAC infrastructure is providing the guidance necessary to develop validated methods."

Dr. Alexis Eberendu, lead researcher on the paper, states that "Aloe vera inner leaf gel has been used as a medicinal remedy for many years. Yet some aloe products do not demonstrate beneficial effects, indicating that poor quality products are reaching the market. Therefore, an efficient and accurate method is needed to evaluate the quality of aloe products. The method we have developed is inexpensive, simple, sensitive, and reproducible, both qualitative and quantitative information can be obtained in about 5 minutes."

Dr. Bill McAnalley, Chief Science Officer for Mannatech stated that he believes "This will move the industry toward standardization and provide the public the confidence needed to purchase aloe products, knowing that they are getting what they think they are getting."

According to the AOAC website,, "When the Federal Drug Administration (FDA) imposes regulations on dietary supplements; they will require analysis by validated, proven, reliable methods. Having these methods already in place will be a huge step toward compliance." There are no federal assays on this subject, so validation and acceptance of analytical methods on aloe vera will allow both the FDA and the industry to measure the quality and purity of product claims and to eliminate inferior products from the marketplace.

In addition to Dr. Eberendu authoring this scientific assay, Gabriela Luta, Joshua A. Edwards, Dr. Bill H. McAnalley, and Bryce Davis of Mannatech, Incorporated, and Santiago Rodriguez of Lorand Lab, as well as C. Ray Henry of American Global Health Group, also contributed to the assay.

About Mannatech

Based in Coppell, Texas, Mannatech, Incorporated is a wellness solutions provider that develops innovative, high-quality, proprietary nutritional supplements, topical products and weight management products, which are sold through a global network marketing system throughout the United States and the international markets of Canada, Australia, the United Kingdom, Japan, New Zealand, South Korea and Taiwan.

About AOAC

"AOAC INTERNATIONAL is an independent, not-for-profit scientific association dedicated to the development and validation of analytical standards. AOAC is currently working under contract with the National Institutes of Health and with the dietary supplement industry to get inferior products off the market through the sound, science-based solution of standardized testing methodology."

Please Note: This release contains "forward-looking statements" within the meaning of Section 27A of the Securities Act of 1933, as amended, Section 21E of the Securities Exchange Act of 1934, as amended, and the Private Securities Litigation Reform Act of 1995. These forward-looking statements generally can be identified by use of phrases or terminology such as "may," "believes," "estimates," "projects," " well positioned," "feels," and "plans" or other similar words or the negative of such terminology. Similarly, descriptions of Mannatech's objectives, strategies, plans, goals or targets contained herein are also considered forward-looking statements. Mannatech believes this release should be read in conjunction with all of its filings with the Securities and Exchange Commission and cautions its readers that these forward-looking statements are subject to certain events, risks, uncertainties, and other factors. Some of these factors include, among others, Mannatech's inability to attract and retain associates and members, increases in competition, litigation, regulatory changes, and its planned growth into new international markets. Although Mannatech believes that its expectations, statements, and assumptions reflected in these forward-looking statements are reasonable, it cautions its readers to always consider all of the risk factors and any other cautionary statements carefully in evaluating each forward-looking statement in this release, as well as those set forth in its latest Annual Report on Form 10-K, and other filings filed with the Securities and Exchange Commission, including its current reports on Form 8-K. All of the forward-looking statements contained herein speak only as of the date of this release.

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