Medical Research Institute Tests Safety and Efficacy of Nutritional Supplements Using Clinical Studies at Baylor University

SAN FRANCISCO, Nov 16, 2004 (BUSINESS WIRE) -- Medical Research Institute (MRI), today released the results of clinical studies of its NO2(R) supplement. With these studies, conducted at Baylor University's Exercise & Sport Nutrition Laboratory, MRI has thrown down the gauntlet to the rest of the industry by effectively shifting the responsibility of determining safety and efficacy from the consumer to the manufacturer.

NO2, the number one-selling sports nutrition product at General Nutrition Center (GNC) stores nationwide, generates nitric oxide to enhance muscle strength, boost power, and improve muscular endurance when used in conjunction with regular training.

In the double blind, randomized, placebo-controlled clinical studies conducted at Baylor, 35 highly trained males, ages 30 to 49, were required to take either NO2 or a placebo pill during eight weeks of intense training. The study revealed that subjects in the NO2 group improved their power and muscular endurance, while the placebo group lost power and muscular endurance. In addition, subjects in the NO2 group gained 347% more strength on their bench press and, all of these improvements took place without any negative side effects observed. The findings also indicate that non-extended-released and extended-released arginine supplements have different "release profiles" which may affect the effectiveness of oral arginine supplementation in humans.

Four studies were conducted at Baylor University's Exercise & Sport Nutrition Laboratory. "Pharmokinetic Profile of Time Released and Non-Time Released Oral Arginine," "Effects Of Arginine Alpha-Ketoglutarate Supplementation on Body Composition and Training Adaptations," "Effects of Arginine Alpha-Ketoglutarate Supplementation on Markers of Catabolism and Health Status" and "Effects of Arginine Alpha-Ketoglutarate Supplementation on Quality of Life."

About NO2(R)

MRI's best-selling NO2(R) has created a revolutionary new category of performance-enhancing supplement known as nitric oxide generators. Through mediation of the "signaling-molecule" nitric oxide (NO), NO2 induces vasodilation and creates dramatic increases in lean muscle mass, strength, and endurance. And with its patent-pending controlled-release delivery technology, NO2 generates a lasting muscle pump that is commonly referred to as the "perpetual pump."

About MRI and MRI Products

MRI is a leading provider of sports nutraceuticals for individuals in the athletic community and organizations where strength and fitness are essential. The Company extensively researches and develops innovative natural supplements with cutting-edge, controlled-released technology.

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