Verdure Sciences announced a new scientific development on the primary active compounds from Tinofend® Extract, a key botanical extract derived from Tinospora cordifolia used to promote optimal immune response.
Polysaccharides linked to immunosupportive properties were detected in significant and consistent quantities in Tinofend® during VBATS™ Analysis (1). The total polysaccharide fraction from Tinofend, comprising no less than 20% of the total extract, was measured and validated for sensitivity, specificity, and precision using AOAC guidelines for single lab validation (2,3). This assay adds a key point of control to a list of stringent physical and chemical specifications for Tinofend.
“Natural products, especially botanicals, are subject to variation in composition. Therefore, standardization is of utmost importance to ensure consumers receive the same benefits found in clinical trials,” said Blake Ebersole, Technical Director of Verdure Sciences. “This is why we have dedicated substantial time and resources to characterize botanical ingredients, and are continuously working towards developing and validating suitable analytical methods for their standardization.”
This development follows randomized, placebo-controlled clinical research on Tinofend that indicated a clinical benefit on various immune-related endpoints in just two weeks (4,5). Polysaccharides are researched as the primary active component of Tinospora along with other immune health ingredients such as Echinacea, Astragalus, and medicinal mushrooms.
Tinofend® is manufactured in Verdure Sciences’ cGMP-registered, botanicals-only facility, and adheres to the strictest international quality standards.
About Verdure Sciences:
Verdure Sciences offers innovative bionutritionals through the integration of agricultural networks, manufacturing control, and university-based, cutting-edge research. With an expanding pipeline of proprietary, standardized botanical ingredients supported by pharmacokinetic, pharmacodynamic, and clinical research profiles, we work toward our unified vision to offer access to safe, effective health solutions.
1. Verdure Botanical Active Testing System™ (VBATS™). Source: http://www.vs-corp.com/VBATS.html
2. AOAC Guidelines for Single Laboratory Validation of Chemical Methods for Dietary Supplements and Botanicals. Source: http://www.aoac.org/Official_Methods/slv_guidelines.pdf
3. Method validation for the quantification of total polysaccharides in Tinofend® Extract, Verdure Sciences 2011.
4. Badar V.A. et al. Journal of Ethnopharmacology 2005 (96); 445-449.
5. Thawani V.R. et al. The Antiseptic 2006 103(4); 229-232.