A recently completed placebo controlled double-blind human clinical trial has shown that consuming a combinations of conjugated linoleic acid and green tea extract for a period of 12 weeks resulted in a significant loss of body weight in overweight human subjects. Results from this study are now being submitted for publication to a scientific journal.
Dr. Venket Rao, Professor Emeritus Department of Nutritional Sciences, University of Toronto and Dr Kathee Andrews, MD conducted the trial to evaluate the effect of ingesting the product abs+, which contains the two active ingredients conjugated linoleic acid (CLA) and epigallocatechin gallate (EGCG) at levels previously shown individually (see fact sheet attached) to bring about changes in body weight in human subjects.
“We know that restrictive diets are rarely successful in weight loss efforts,” says Dr. Rao, “so researchers have been searching for safe adjuncts to increase daily energy expenditure. Conjugated Linoleic Acid (CLA) and EGCG from green tea are two such natural ingredients that are not only supported by laboratory testing, but also by human clinical trials.”
A significant reduction in the body weight of subjects ingesting abs+ compared to placebo was observed: close to 60% of the subjects in the placebo group either gained weight or had no change during the course of the 12 weeks, whereas in the abs+ group 70% of the subjects either lost weight or had no change in their body weights.
This observation may have significant implications for the management of body weight-related health risks. Products such as abs+, as part of a healthy diet and life style, can offer an effective alternative to restrictive diets in the maintenance of ideal body weight and also to achieve weight loss in the case of obesity,” said Dr. Rao.
Thirty four human subjects, male and female, over 30 years of age having a BMI of 25 or more and a waist circumference of 80cm or more for females and 94cm or more for males, were assigned randomly to either a control group who received six placebo capsules containing no active ingredients or a treatment group who received six abs+ capsules each containing 576mg CLA and 45mg of EGCG for a total daily intake of 3,400mg CLA and 270mg EGCG.
Subjects ingested the placebo or the abs+ capsules for a period of 12 weeks. Body weight, waist circumference and percent body fat were measured at the end of 0, 4, 8 and 12 weeks.
abs+, from ehn inc., the makers of greens+, is a unique formula that includes two ingredients, both of which have been shown to lead to weight loss in human clinical trials. The dosages in abs+ have been carefully set to match those used in these effective human trials. For more information visit www.greenspluscanada.com.
Conjugated Linoleic Acid (CLA)
CLA is a naturally occurring derivative of the Omega-6 essential fatty acid, linoleic acid, naturally found in a number of foods, but most specifically in fish, beef, whole milk and butter. Research indicates that an effective adult dose for weight loss is 3,400mg of pure CLA daily (the amount found in 6 abs+ soft gels).
In order to achieve this amount of CLA through the diet alone, one would also have to consume a large number of calories (and other unhealthy fats) that promote weight gain.
Other CLA research includes human trials and a number of high quality, controlled human studies. They have shown that CLA can reduce body fat. These results have also been published in prestigious medical journals such as the Journal of Nutritional Biochemistry 2001, Journal of Nutrition 2000, Lipids 2001 and the Journal of International Medical Research 2001.A particularly significant double-blind, randomized, placebo-controlled study with CLA, published in the International Journal of Obesity, found an average reduction of one inch to the waistlines of 25 men over a four week study period, with no cardiovascular risk or other side effects.
Green tea standardized to EGCG catechins:
Green tea has been used for centuries as a medicinal agent and beverage. Recent scientific investigations have shown that green tea contains potent antioxidants, enhances immunity and is protective of the heart. The important natural chemicals in green tea which promote health and weight loss appear to be the polyphenols– in particular a catechin called epigallocatechin gallate or EGCG that cannot be found in significant amounts in any other food sources.
Research indicates that green tea can safely enhance thermogenesis, increasing 24-hour energy expenditure. Simply put, it can increase calories burned through fat breakdown. Research published in the American Journal of Clinical Nutrition (1999) showed that green tea (containing 90mg of EGCG) could lead to a 43% increase in thermogenesis in adults, an increase that could not be attributed to the caffeine in green tea. Additional research published in the International Journal of Obesity (2000) and Phytomedicine (2002) highlights the ability of green tea to increase the burning of fat as fuel and resulting human weight loss.