Part 5: Science, Research and Technology

[9/30/2005] Two Seminal Studies Demonstrate Benefit of Glucosamine And Chondroitin In Osteoarthritis Patients
National Institutes of Health (NIH) trial shows effectiveness of glucosamine/chondroitin combination for moderate to severe pain, while multi-center European study favorably compares glucosamine to over-the-counter remedy for joint pain.
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[9/28/2005] In-vitro Study shows ReGen's Colostrinin(TM) increases lifespan of Mouse Cells Predisposed To Premature Ageing
UK-Base ReGen Therapeutics Plc announces the results of an in-vitro study showing that ColostrininTM increases the lifespan of cells isolated from inbred mice predisposed to premature ageing and therefore, death.
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[9/27/2005] Analysis Indicates Eighty-five Percent of Postmenopausal Women Not Getting Adequate Calcium
According to an article on, citing an analysis presented at the Annual Meeting of The American Society for Bone and Mineral Research, pooled results from six Phase III osteoporosis trials (11,474 postmenopausal women) indicates that on average, women consumed almost 500mg less than the US Recommended Daily Intake of calcium of 1200mg/day for women aged 50 or more.
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[9/27/2005] Pomegranate Juice Shows Promise In Lab,To Combat Prostate Cancer
According to an article on, University of Wisconsin researchers have noted a dose-dependent effect of pomegranate extract on human prostate cancer cells, as well as slowing of cancer progression and decrease in prostate-specific antigen (PSA) in mice supplemented with .2% pomegranate extract.
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[9/27/2005] Neuroprotective Effect of Palm Tocotrienols Studied
According to an article on, research presented at the International Palm Oil Congress (PIPOC) suggests that palm tocotrienol is associated with protecting brain cells from glutamate-induced toxicity, and is more effective than regular alpha-tocopherol found in most Vitamin E preparations as it was found to cross the blood-brain barrier as a neroprotective agent.
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[9/26/2005] South Africa: Research Center Awarded Grant
According to an article on South Africa's, a research consortium led by the SA Herbal Science and Medicine Institute (SAHSMI) at the University of the Western Cape (UWC) and the Missouri University School of Medicine, has been awarded R24.5 million (~$3.85 million USD) for the development of a new research center, the International Centre for Indigenous Phytotherapy Studies for Aids, Secondary Infections and Immune Modulation.
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[9/23/2005] Study Shows Higher DHA Levels in Breast Milk Benefit Newborn Behavior
researchers at Texas Tech University, in a study published in this month's Journal of Pediatric Psychiatry have determined a correlation between DHA (docosahexaenoic acid) levels in breast milk and newborn neurobehavioral function in an examination of breat milk collected from 20 breastfeeding mothers 9 days after delivery.
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[9/23/2005] Mexico: Researchers Examine Health Benefits of Blue Agave Plant
According to a Reuters article, researchers at Mexico's University of Guadalajara are investigating properties of the juice extracted from the blue agave plant, source of the distilled liquor known as tequila. According to the article, the researchers have determined that the juice contains fructans, and in animals, fructans affect fat absorption in the intestine. The researchers have initiated human studies to determine whether the effects are similar and if there are potential applications for weight management. The article notes that the potential health benfits are lost when the product is distilled.
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[9/22/2005] Kanda Clinic Begins Investigative Human Clinic Trials With Graminex G63™ Pollen Extracts
US-based botanical ingredient company Graminex L.L.C. has announced that Dr. Hiromi Yokoyama, principle of Japan's Kanda Ishin Clinic is set to begin investigative human clinical trials with Graminex G63(TM) Pollen Extracts for various health treatment applications.
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[9/21/2005] Biogaia's Reuteri Reduces Level Of Helicobacter Pylori Infection
Sweden-based biogaia AB has announced results presented at the 3rd Probiotics, Prebiotics New Foods Congress in Rome which indicate that in a placebo controlled study of 20 adults with H. pylori infenction, the company's probiotic Reuteri reduced the level of H. pylori infection, alleviated gastrointestinal symptoms caused by the infection and reduced the side effects of antibiotic treatment.
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[9/21/2005] Study: Green Tea Effective Against Alzheimer's Disease
Researchers at the University of South of Florida , in an article published in the Journal of Neuroscience, observed that epigallocatechin-3-gallate (EGCG) in green tea, in a mouse model, decreases production of the Alzheimer's-related protein, beta-amyloid, which can accumulate abnormally in the brain and lead to nerve damage and memory loss.
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[9/21/2005] Australian Researchers Examine Fish Oil Anti-Depressant Link
According to an article in The Australian, researchers at Sydney, Australia's Black Dog Institute are recruiting patients with mild depression to participate in a 14 week, placebo controlled, crossover study to examine whether fish oil supplements are effective in treating depression. According to the article, the fish oil product to be used in the study contains higher doses of Omega-3 than generally available in over-the-counter dietary supplements.
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[9/21/2005] Australia: Fish Oil and Primrose Oil Studied in Children with ADHD
According to an article on MedicalNewsToday, citing research from Australia (University of South Australia and CSIRO Nutrition) presented as part of the Fresh Science program for early career researchers, parents of children on a 15 week regimen of fish oil and primrose oil reported increased attention, reduced hyperactivity, restlessness and impulsivity in the children.
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[9/19/2005] Probiotics: 2nd Generation Products Will Expand Market Beyond Yogurt
Denmark-based Chr. Hansen, with the company's new Direct Liquid Inoculation solution, is proposing to add healthy bacteria to the milk or juice after heat treatment in a closed and sanitary system, in order to make safe probiotic beverages in a flexible manner and using their existing equipment. According to the company, this makes chilled beverages such as orange juice likely candidates in the next probiotic market development.
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[9/19/2005] Survey Indicates that Consumers Would Buy Oat Products to Help Lower Cholesterol
A recent survey of 1,000 adults conducted The Natural Marketing Institute, for Nurture, Inc., makers of OatVantage(TM) oat bran ingredient, indicates that three times as many consumers would buy products to help lower cholesterol if they are made from oats versus a product that just states “clinically proven to reduce cholesterol". The survey indicates that 46% of all consumers would be more motivated to purchase products to manage their cholesterol if they are made from oats, compared to only 17% who would purchase products “clinically proven to reduce cholesterol.”
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[9/15/2005] New Study Suggests Chromium Picolinate Triggers Key Enzyme to Improve Glucose Metabolism
Research conducted by the Pennington Biomedical Research Center, and presented at the 41st Annual Meeting of the European Association for the Study of Diabetes (EASD) in Athens, Greece, indicates that chromium picolinate may increase the amount of AMP-activated protein kinase (AMPK) -- a key enzyme involved in metabolism -- in skeletal muscle cells, thus improving energy balance and insulin function. The chromium picolinate used in this study was provided by Nutrition 21, the makers of Chromax(R) chromium picolinate.
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[9/15/2005] Study Shows Walnuts Are a Potent Source of Melatonin
Research at The University of Texas Health Science Center in San Antonio, published in the September issue of Nutrition, found walnuts are a potent source of melatonin. The California Walnut Industry provided a grant to support this research.
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[9/15/2005] Breast milk alternative may prevent food allergies
According to a Reuters Health article citing a report in this month's issue of Archives of Pediatrics and Adolescent Medicine which reviews studies on the subject, observing that high-risk infants who consumed extensively hydrolyzed casein formulas or partially hydrolyzed whey formulas had a lower rate of food allergy for up to 5 years after birth than did those fed cow's milk-based formulas. According to the article, the researchers reviewed a total of 22 studies.
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[9/13/2005] Researchers Examine Role of DHA Derivative
According to research published online in the Journal of Clinical Investigation, researchers at Louisiana State University have investigated how docosahexaenoic acid (DHA) acts to protect against cognitive decline associated with Alzheimer's disease, and specifically how a derivative of DHA ("neuroprotectin D1" (NPD1)), which also plays a key role, is made. NPD1, the researchers conclude, promotes brain cell survival by altering gene expression, reducing proinflammatory response.
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[9/13/2005] Research Examines Effect of Vitamin C on Cancer Cells
According to an article in WebMD citing research published in Proceedings of the National Academy of Sciences (Sept. 20, 2005; vol 102: pp 13604-13609), lab tests indicate that vitamin C, introduced into cells, boosted production of hydrogen peroxide which in turn killed the cancer cells while leaving the healthy cells unharmed. According to the researchers the levels of vitamin C needed could only be achieved through intravenous infusion. Currently a safety study on this application is underway.
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[9/13/2005] Study Shows Cinnulin PF Promotes Increase in Lean Body Mass and Reduction in Body Fat
A double blind, placebo controlled clinical study conducted by the Ohio Research Group on Cinnulin PF(R) indicated that subjects in the Cinnulin PF group noted statistically significant increases in lean body mass and reduction in overall body fat, compared to the control group.
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[9/13/2005] Study Examines Correlation Between Soy Protein Consumption and Bone Fracture Risk
According to a Reuters article citing a report published in the Archives of Internal Medicine, researchers sampled 24,000 women participating in the three-year Shanghai Women's Health Study and found that those who ate the most soy protein had a 37% lower risk of bone fracture compared to women who consumed the least soy. According to the article, the sample was grouped into five with those eating at least 13 grams per day at one end, and the low-consuming group eating 5 grams per day.
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[9/12/2005] Blue Heron Nutraceuticals, LLC, publishes Muscadine Medicine
Blue Heron Nutraceuticals, LLC, has announced the publication of Muscadine Medicine, written by three biomedical researchers who direct nutraceutical research laboratories at the University of Georgia. The publication cites 482 biomedical research papers from top scientific and medical journals concerning the nutraceutical value of American muscadines and scuppernongs (Vitis rotundifolia).
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[9/9/2005] Two Studies Examine Nutratech's Advantra Z(R) for Safety and Efficacy
A randomized, double-blind, placebo-controlled study on 10 individuals conducted at the University of California, San Francisco, published in September's American Journal of Medicine examined the cardiovascular actions of Advantra Z(R), Nutratech's proprietary Citrus aurantium (bitter orange) extract, observing that the product had no effect on blood pressure and produced an increase in heart rate of on average 11 beats per minute. A second study, published in the July issue of Obesity Research, entitled "Increase in the Thermic Effect of Food in Women by Adrenergic Amines Extracted from Citrus Aurantium,", using Advantra Z, determined efficacy and noted that thermic response to Citrus aurantium was higher in men when taken alone and more efficacious for women when added to a meal. A release issued by UCSF does comment on the health issues raised by the UCSF study, which actually employed two bitter orange-based products, noting the increase in heart rate and observing that the second product used, Xenadrine EFX, was associated with a 7 to 12% increase in blood pressure.
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[9/8/2005] NutriCognia Launches LactoFact(TM) - Lactoferrin Glyco-Analysis Assay
NutriCognia, a member of Israel-based Solbar Group has announced the launch of Lactofact(TM) - a rapid lactoferrin glyco-analysis kit targeted at the dairy inudstry, to control the production process and product development as well as improving quality control procedures. According to the company, LactoFact ™ is based on CarboDeep™, a proprietary technology that compares glycan mixtures and produces a fingerprint of the glycan composition.
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[9/6/2005] New Research Shows That Folic Acid Fortification Has Significantly Reduced Serious Birth Defects
According to an article on citing research published in the journal Pediatrics, researchers at the U.S. Centers for Disease Control and Prevention (CDC) reported that folic acid fortification accounted for a 36% decline in neural tube defects in the Hispanic population and a 34% drop among the white, non-Hispanic population between 1995 and 2002. An accompanying editorial calls on the FDA to at least double the amount of folic acid required in enriched grain foods (currently set at 140 micrograms of folic acid per 100 grams of grain).
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[9/6/2005] Mushrooms Good Source for Anti-Oxidant Compound
According to an AP article in the Pittsburgh Tribune Review, researchers at Penn State University, in a study to be presented at a meeting of the American Chemical Society in Washington, have observed that white button mushrooms have about 4 times more of the antioxidant ergothioneine than chicken liver, and about 12 times more ergothioneine than wheat germ, while exotic mushroom varieties contain about 40 times more than wheat germ.
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[9/6/2005] Study Indicates B Vitamins not Cardioprotective
According to an article on BBC News citing research at a European Society of Cardiology meeting, The Norwegian Vitamin Trial (NORVIT) examined 4,749 heart attack survivors who, in addition to their standard heart medication, received either daily folic acid, daily vitamin B6, both folic acid and vitamin B6 or a dummy drug for three years, observing that those who had been taking either folic acid or vitamin B6 alone had a small increase in the risk of cardiovascular disease (heart attack or stroke), compared with those who had received the placebo. Those who had taken both folic acid and vitamin B6 each day had a 20% increased risk of heart attack and stroke, despite their homocysteine levels going down by up to 30%.
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[9/2/2005] Researchers Observe That Compound in Olive Oil has Anti-inflammatory Effect
According to an LA Times article on, scientists at the Monell Chemical Senses Center in Philadelphia, in research published in the journal Nature, note that a compound in olive oil, oleocanthal, inhibits the activity of cyclooxygenase enzymes, the same anti-inflammatory effect of ibuprofen. According to the article, the highest olecanthal levels are found in olives from Tuscany and the lowest in many California olive groves.
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[9/1/2005] Study: Pomegranate Fruit Extracts Can Block Enzymes That Contribute to Osteoarthritis
According to an article on News.Medicalnet citing a study published in the Journal of Nutrition, researchers, using tissue samples, examined the ability of pomengranate (water) extract against Interleukin-1b (IL-1b), a pro-inflammatory protein molecule that plays a key role in cartilage degradation in osteoarthritis. The researchers observed that the extract inhibited the overproduction of matrix metalloproteases (MMP) enzymes in human cartilage cells, created by IL-1b protein molecules, indicating the extract might have the potential to suppress cartilage degradation in osteoarthritis.
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