Preliminary research reveals Cognitex's cognitive benefits

Preliminary research reveals Cognitex's cognitive benefits

Life Extension's Cognitex with NeuroProtection Complex may improve cognitive performance in middle-aged to elderly subjects with subjective memory complaints.

Life Extension Foundation of Fort Lauderdale, Fla., a pioneer in funding and reporting the latest anti-aging research and integrative health therapies, has announced positive results from its study to assess the effectiveness of the dietary supplement, Cognitex with NeuroProtection Complex, in improving cognitive performance in middle-aged to elderly subjects with subjective memory complaints.

The study, conducted at Life Extension Clinical Research, Inc. in Fort Lauderdale, Fla., assessed the change in cognitive performance from baseline to day 30 and day 60, based on taking the online cognitive assessment tool, computerized neuropsychological test, results from a CGI-I (Clinical Global Impression Improvement) scale and an assessment survey for consumer attitude.

Forty middle-aged to elderly subjects were enrolled and given three capsules per day of the dietary supplement. Cognitive evaluations were conducted at various time points. The results yielded a score measuring different cognitive capabilities. The CGI-I scale provided an overall clinically determined summary measure.

Twenty-nine subjects completed the study with no significant adverse events being reported. Preliminary results revealed a statistically significant improvement in three tests. Working Memory-N-Back displayed the most significant improvement (p<0.0001), as well as inspection time and executive function (p<0.05). Based on the CGI-I Scale, improvement was noted after 30 days and 60 days of product use.

“Data demonstrated that the combination dietary supplement product Cognitex with NeuroProtection Complex may provide a positive impact on cognitive performance, including improvements in working memory-n-back, which is a key cognitive function used daily, as well as in inspection time and executive function,” said Dr. Steven Hirsh, Life Extension clinical research director of clinical research. “The results attained through the CGI-I scale reflected an overall improvement in the subjects following administration of the study product.”

Dr. Hirsh and Dr. Susie Rockway, executive director of product development for Life Extension, presented the study at the Experimental Biology 2012 multidisciplinary scientific conference in San Diego, Calif., April 21-25. After successful submission of the abstract to the conference, a poster presentation for the clinical research project was conducted at the conference. 

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