The Women's Health Study (WHS), the largest, long-term, randomized vitamin E trial ever conducted, has revealed that vitamin E significantly reduced the risk of death from major cardiovascular events (e.g., heart attack or stroke) by 24 percent. A 10-year study of nearly 40,000 healthy women, WHS also showed that for women age 65+, vitamin E's effect was even greater: a 49 percent decrease in the risk of cardiovascular death and a 34 percent reduction in heart attacks.
The findings were published in the July 6 edition of the Journal of the American Medical Association, JAMA.
These findings also indicate that Vitamin E is safe, with participants taking 600 IU of Vitamin E supplements every other day without an increase in total mortality in healthy women.
This study refutes a meta-analysis of 19 previous studies published late last year which appeared to indicate an increase in mortality, but the meta-analysis results focused on already ill, high, risk populations rather then healthy subjects.