Superba Krill Oil study shows positive impact on fat signaling markers in obese humans

Aker BioMarine announces the publication of a new study investigating the effect of krill oil on the endocannabinoid (EC) system in humans. The EC system is comprised of a group of lipids (fats) and receptors that act within the nervous system to help modulate a number of physiological processes including appetite and mood, among others. In this study, normal weight, overweight, and obese subjects were given two grams of krill oil, menhaden fish oil, or olive oil per day for four weeks.

Aker BioMarine announces the publication of a new study investigating the effect of krill oil on the endocannabinoid (EC) system in humans. The EC system is comprised of a group of lipids (fats) and receptors that act within the nervous system to help modulate a number of physiological processes including appetite and mood, among others. In this study, normal weight, overweight, and obese subjects were given two grams of krill oil, menhaden fish oil, or olive oil per day for four weeks. Obese persons have elevated levels of plasma ECs compared to normal weight individuals, which was confirmed in the current study. The results demonstrate for the first time that a relatively low dose of omega-3 fatty acids (< 400 mg EPA + DHA), have beneficial effects on EC levels in obese persons when given in the form of krill oil.

According to Nils Hoem, PhD, Chief Scientist at Aker BioMarine, “This is an important finding confirming previous outcomes with krill oil in obese animals. Helping  ormalize endocannabanoid levels in obese subjects may help address potential long-term health issues, including metabolic syndrome, though these are preliminary findings and additional research is necessary to draw solid conclusions. However, it is important to note that the study suggests that phospholipid form of omega-3 fatty acids found in krill oil was responsible for the beneficial effects observed in this study.”

Published in Nutrition & Metabolism, (Nutrition & Metabolism 2011, 8:7) the study confirms previous findings showing that krill oil has beneficial effects on the EC system in an animal obesity model. SuperbaTM Krill Oil provides the majority of its omega-3 fatty acids in the form of phospholipids, whereas other common marine oils contain omega-3 fatty acids in the form of triglycerides or ethyl esters. This work was performed in cooperation with internationally acknowledged researchers in Finland, Italy and USA, and the location of the clinical trial was at Provident Clinical Research, Glen Ellyn, Illinois, USA.

Omega-3 phospholipids are considered to be an effective system for delivering the omega-3 fatty acids EPA and DHA to tissues. In fact, in vivo and human research with phospholipid EPA & DHA from krill oil demonstrates higher uptake of omega-3 fatty acids in red blood cell membranes (omega-3 index), improved blood lipid profiles, and increased uptake of DHA in brain tissue compared to other omega-3 fatty acid sources.

Aker BioMarine is the only krill ingredient marketer that is primary in its supply, providing traceability from its vessel harvesting krill in the pristine Antarctic Ocean through the proprietary manufacture of krill ingredients. The proprietary Eco- arvesting™ technology with processing on the vessel and novel extraction process results in the unique composition of Superba™Krill Oil. SuperbaTM Krill Oil thus provides the highest harvesting and manufacturing controls from the sea to shelf. Aker BioMarine is the only krill harvester that has been awarded Marine Stewardship Council (MSC) Certification. Banni, et. al., Krill oil significantly decreases 2-arachidonoylglycerol plasma levels in obese subjects. Nutrition & Metabolism 2011, 8:7 is available online at: www.nutritionandmetabolism.com/content/8/1/7.

About SuperbaTM Krill Oil

SuperbaTM Krill Oil is a pure, natural source of the health-promoting EPA & DHA omega-3 essential fatty acids and the naturally occurring antioxidant astaxanthin. The uniqueness of SuperbaTM Krill Oil is that the omega-3 fatty acids are provided in phospholipid form. In vitro, in vivo, and human clinical research has demonstrated the safety and efficacy of SuperbaTM Krill Oil.

About Aker BioMarine

Aker BioMarine is an integrated biotechnology company dedicated to the sustainable harvesting of krill and development of krill-derived biotech products. The company supplies biomarine ingredients through an optimized value chain from raw materials to customers. Aker BioMarine's SuperbaTM Krill products are provided with 100-percent traceability from the Antarctic sea to the end user. Only Aker’s krill fishery has been awarded Marine Stewardship Council (MSC) Certification.

For more information, please contact:

Nils Hoem, Chief Scientist, Research and Development, Aker BioMarine, +47 24 13 00 00. Matts Johansen, EVP Sales & Marketing, Aker BioMarine, +47 24 13 00 00.

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