Yale study finds weight loss starts in brain, not on plate

Yale study finds weight loss starts in brain, not on plate

A Yale University study published in the Journal of Clinical Investigation that found obesity is affected by how well a control system in the brain is working.

The Swiss pharmaceutical company that develops the slimming spray SENSASLIM, which is widely called "the model's miracle" due to its popularity with supermodels and celebrities, says its 20 years of obesity research has been reinforced by a Yale University study published in the Journal of Clinical Investigation that found obesity is affected by how well a control system in the brain is working.

U.S. researchers Dr. Kathleen Page and Dr. Dongju Seo from Yale University, along with researchers from the University of Southern California, have found the brains of normal-weight and obese people react differently to pictures of energy-rich foods, with obese people having less activation in a brain area that can inhibit cravings.

SENSASLIM Research Director Dr. Sommerville said, "This may prove to be an important clue to understanding obesity and supports our research that the more effective ways to curb weight gain is by beginning not on the plate but in the brain."

"What happens in lean people, when their blood sugar is not dropping, is that their executive function lights up - the area involved in making decisions," explains Robert Sherwin, Professor of Medicine at Yale and senior author of the paper.

The implication, he says, is that there is a biological driver that pushes obese people to continue to eat, even when they're full. They may not "see" food the same way as lean people do, because their reward and desire signals are consistently signaling that they want to eat, and that they want to eat high-calorie foods in particular.

Dr. Sommerville says it is as if normal-weight people are saying to themselves, "Hmmm, I've had enough I think" - but obese people do not have that inhibition: "The discovery that obese people are not getting the inhibition from their executive control centre is exciting."

Dr. Sommerville said SENSASLIM Slimming Spray could "give will power to the weak."

"SENSASLIM removes the call of action to eat, by fooling the brain into believing that you are full. This is achieved through the taste buds, which are pleasantly desensitized by a natural herb. This sends a message to the brain that suppresses the appetite, without affecting the central nervous system," he said.

"In simple terms, if you don't think of food, you don't crave food - you don't eat food. The weight just drops off."

The success of SENSASLIM saw fashion models in China this week ask the slimming company to rescue 10-year-old Le Le, who at 155 kilograms weighs almost four times more than other boys his age. He has been diagnosed with a compulsive eating disorder, has developed a fatty liver and is gorging himself to an early death.

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