Mouse Study Confirms Peptan™ Hydrolyzed Collagen Benefits on Bone Health

Previous in vivo and in vitro studies carried out with Rousselot Peptan™ Hydrolyzed Collagen and published in the March 2010 issue of “BONE” have demonstrated the positive effect of this ingredient on bone cells (osteoblasts) and on bone matrix.

At the IOF World Congress on Osteoporosis, Rousselot presented two new in vivo experiments that were aimed at defining the action of Peptan™ Hydrolyzed Collagen on bone health.

These studies were performed on ovariectomized mice, which are a good model for post-menopause osteoporosis. The mice received a daily intake of Peptan™ during up to 24 weeks. Bone mineral density (BMD), CTX bone resorption marker and biomechanical properties of the bones were then measured.

The results fully confirm the positive effect of a daily intake of Peptan™ Hydrolyzed Collagen that had already been observed in previous studies. BMD is significantly higher in mice receiving a Peptan™-enriched diet than in the control group which did not receive Peptan™. Likewise, the bone resorption marker CTX is lower and bone strength is greater when the mice are fed Peptan™.

Finally, these studies have shown that Peptan™ has a preventive effect on bone loss when given to the mice pre- ovariectomy. Peptan™ has also demonstrated a similar effect to raloxifene, a pharmaceutical used for post-menopausal osteoporosis.

These new findings confirm the very great advantage of Peptan™ Hydrolyzed Collagen for bone health and for preventing age-related bone loss.

During the Vitafoods trade show, Geneva, 18-20 May 2010, Rousselot will be on stand N°858, presenting detailed results of these studies and the other health benefits on skin and joints associated with Peptan™ Hydrolyzed Collagen.

About Rousselot®
Part of VION N.V. (N.L.), Rousselot® is the leading manufacturer of gelatine and hydrolyzed collagen for the food, pharmaceutical and technical industries. With a staff of 2,400 people, the company benefits from a global sales and production network of 12 plants and 10 sales offices located in Europe, North America, South America and Asia.
VION N.V.: VION N.V. is an international food company with production and sales operations on all continents. The company is active in the fields of high-quality foodstuffs and ingredients for people and animals. The company has two core activities: VION Food and VION Ingredients. VION has an annual turnover of € 9.6 billion and employs 31,000 people worldwide. The VION head office is in Son en Breugel, the Netherlands.

More information: Caroline Brochard-Garnier - Communication Manager. - Téléphone: +33 1 46 67 87 27. - E-mail: [email protected] - Caroline Nègre – Brand and Marketing Manager - Téléphone: +33 1 46 67 87 25. E-mail: [email protected]

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