New Study: CLA May Serve Critical Role in Preventing Weight and Fat Gain During Year-End Holidays and with Normal Aging

Research Shows Tonalin® CLA Effective When Adults
are Susceptible to Adding Weight and Fat

La Grange, IL (Aug. 15, 2006) – A new study1 published online today in the prestigious International Journal of Obesity suggests that Tonalin® CLA could have long-term health benefits by preventing weight and fat gain commonly experienced by adults during the November-December holiday season, and in the normal aging process.

Cognis' Tonalin® CLA (conjugated linoleic acid) is derived from natural safflower oil, is stimulant-free, and is the most clinically tested CLA on the market.

“These findings suggest that CLA may serve a critical role in reducing a common weight and fat gain that occurs with age,” said Prof. Dale Schoeller, Ph.D., University of Wisconsin-Madison, and an author of the study. “About 65 percent of the U.S. population is obese or overweight—that’s a dangerous trend on many levels. We need more research like this to help overweight individuals when they are susceptible to weight gain.”

Researchers at the University of Wisconsin-Madison recognized that “small, often cumulative weight gains during the holiday season contribute to ‘weight creep’ during adulthood.” They designed a study to determine if Tonalin® CLA supplementation would help overweight adults significantly reduce body fat over a six-month period and prevent weight gain during the holiday season.

Their findings showed that participants taking Tonalin® CLA safely reduced their body fat mass by 2.2 pounds and their body weight by 1.3 pounds. In comparison, those in the placebo group gained 1.5 pounds of body fat mass and 2.4 pounds of body weight during the months that are especially problematic for overweight individuals.

The study confirmed that taking CLA decreases body fat mass, maintains lean body mass, and aids weight management. Unlike many other studies on body composition, participants in this trial were not restricted by a controlled diet. Furthermore, CLA was well-tolerated among participants taking it for six months just as in earlier one- and two-year trials.

Study subjects included 40 healthy, overweight men and women who took 4 grams of Tonalin® CLA or a placebo per day from August 2004 to March 2005. Participants followed “healthy lifestyle” advice and Dr. Schoeller explained that while adults in this trial were only moderately active, CLA supplementation can be most effective when taken as part of a daily regimen that includes exercise and a reasonable diet.

Results of this double-blind, randomized, placebo-controlled study corroborate and expand upon earlier findings by Dr. Jean-Michael Gaullier. His studies revealed that CLA reduces body fat mass in overweight but otherwise healthy adults by as much as 9 percent. CLA helped participants in his studies keep off the lost fat during the two-year trial.

In this most recent study report, Dr. Schoeller referred to that research and commented on inconsistent results found in other human CLA studies. He said most of the studies with conflicting findings have been 12 weeks or shorter and thus of “insufficient duration or have utilized body composition methods that are a little less accurate than the currently accepted criterion.” The UW study is the first to use the criterion of four-compartment body composition to more accurately reflect fat changes.

Christine Peggau, Tonalin® CLA Senior Marketing Manager at Cognis, said “This science-based study offers a profound new way to begin tackling the obesity trend. If we can help overweight consumers when they need it most—during the food-filled holiday season and as they age—then this research suggests we will begin to see life-long benefits.”

For more information about Tonalin® CLA or to place an order, visit, call 800.673.3702, e-mail [email protected], or fax 513.482.3576.

About Tonalin® CLA:

Tonalin® CLA is the original brand of CLA and is an exclusively licensed product of the Cognis Group. CLA is a polyunsaturated, conjugated fatty acid that is a natural part of the human diet, found primarily in meat and dairy products. Cognis produces Tonalin® CLA through a proprietary process that converts linoleic acid from safflowers into CLA, providing the highest quality of CLA available. Tonalin® CLA contains the lowest amount of non-naturally occurring isomers, a patent-protected attribute that provides food and dietary supplement manufacturers with the highest levels of ingredients known to be beneficial. Tonalin® CLA is available in several product forms—such as oil and water-dispersible powder—offering manufacturers a broad range of options for their products.

About Cognis:

Cognis ( is a worldwide supplier of innovative specialty chemicals and nutritional ingredients. The company employs about 8,000 people, and it operates production sites and service centers in 30 countries. Cognis has dedicated its activities to a high level of sustainability and delivers natural-source raw materials and ingredients for food, nutrition and healthcare markets, and the cosmetics, detergents and cleaners industries. Another main focus is on products for a number of other industries, such as coatings and inks, lubricants, textiles, as well as agriculture and mining. The company holds a 50-percent stake in the joint venture Cognis Oleochemicals, one of the world’s leading manufacturers of oleochemicals. Cognis is owned by private equity funds advised by Permira, GS Capital Partners, and SV Life Sciences. In 2005, Cognis recorded sales of 3.18 billion euros and an Adjusted EBITDA (earnings before interest, income taxes, depreciation, amortization and exceptional items) of 356 million euros.


1 Watras AC, et al. Int. J. Obes. advance online publication, August 15, 2006 (doi:10.1038/sj.ijo.0803437) (

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