Toyo Bio-Pharma Nu Skin Enterprises And Enter Agreement For Joint Product Research And Development

Japan Market To Benefit from Novel Ingredients and Regulatory Expertise

Century City CA—July 28, 2008— Toyo Bio-Pharma, Inc. (a subsidiary of Toyo Shinyaku, Japan) today announced that the company has signed a memorandum of understanding for a joint research and development relationship with Nu Skin Enterprises, Inc. (NYSE:NUS). To facilitate this relationship, the companies established a new joint venture, NU Toyo Research, Inc., in the United States.

Nu Skin Enterprises is the first direct selling company to have such an agreement with Toyo Bio-Pharma. The companies' collaborative development efforts will focus on sharing scientific and regulatory insights, as well as developing proprietary nutraceutical and cosmeceutical products for Nu Skin sales through its worldwide distribution network.

“We expect this relationship with Nu Skin Enterprises to nicely complement our current expertise in natural health supplements,” said Yoshi Shiraishi, president and chief operating officer of Toyo Bio-Pharma. “We highly respect the industry-leading research and development capabilities of Nu Skin Enterprises. We believe there is a synergy between the two research teams that both companies can benefit from.”

“Toyo Bio-Pharma is a subsidiary of Toyo Shinyaku, which is one of the most reputable supplement and skin care manufacturers in Japan, and we look forward to developing a robust relationship with joint development opportunities,” said Joseph Chang, Ph. D., chief scientific officer and executive vice president of product development at Nu Skin Enterprises. “We are eager to leverage their knowledge of navigating regulatory requirements for skin care and supplements in Japan.”

About Toyo Bio-Pharma
Toyo Bio-PharmaTM ( is a subsidiary of Toyo Shinyaku Co., Ltd., a research-driven manufacturer committed to providing consumers and clients with high-value ingredients derived from nature. With the most advanced instrumentation, continuous research and commitment to quality and integrity, Toyo Shinyaku is pioneering the use of fermentation and culturing to produce beneficial, effective products for use in the nutraceutical, functional food and cosmeceuticals industries. Toyo Shinyaku is Japan's largest developer of FOSHU (Food for Specialized Health Use) products and ODM (Original Design Manufacturer) of supplement and skin care products. Toyo Shinyaku follows rigorous standards of ISO 9001:2000 and ISO 22000:2005, and was one of the first Japanese companies to become Food and Drug Administration (FDA) Good Manufacturing Practices (GMP)-compliant for food products and dietary supplements.

About Nu Skin Enterprises
Nu Skin Enterprises, Inc. is a global direct selling company operating in 47 markets throughout Asia, the Americas and Europe. The company markets premium-quality personal care products under the Nu Skin® brand, science-based nutritional supplements under the Pharmanex® brand, and technology-based products and services under the Big Planet® brand. Nu Skin Enterprises is traded on the New York Stock Exchange under the symbol “NUS.” More information is available at

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