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Can we reverse the effect of fructose?

Can we reverse the effect of fructose?
New research suggests we may be able to reverse the harmful effects of fructose in just nine days.

It's October - wish you could undo the effects of your Halloween candy binge later this month? You might be able to, according to new research. OK, your teeth may still rot and you'll never get back the hour you lost to the sugar crash nap you snuck in your cubicle, but you might actually be able to undo the effects of the fructose.

Researchers at Touro University, California and the University of California, San Francisco found that the potentially harmful effect of excessive fructose in our diet can start to be reversed in just nine days, according to a Touro University release.

“These preliminary findings demonstrate how rapidly we can turn things around in our bodies to live healthier and longer lives,” said Shelley Berkley, CEO and Senior Provost of Touro Western Division.

For the study, adult subjects stayed in a research ward at San Francisco General Hospital for 18 days. Researchers carefully monitored their diets, and weighed subjects daily. They swapped fructose calories out for the same number of calories in complex carbohydrates. Researchers were able to isolate fructose, and not overeating, as the key factor. On a related note, a 2013 study published in JAMA blasted fructose (not glucose) for leading to weight gain.

“The preliminary findings of this study help educate the public on the effects of restricting fructose in your diet,” said Dr. Jean-Marc Schwarz of Touro University California, the lead investigator of the study, said in the release. “In this case, overeating is not the culprit. Our research suggests that a high- fructose diet alone can contribute to health problems like cardiovascular disease, diabetes, obesity and fatty liver disease.”

“The positive news is that the potential harm of a high-fructose diet can be quickly reversed, according to researchers,” said Dr. Kathleen Mulligan of the University of California, San Francisco, and adjunct professor at Touro University California, who also worked with Schwarz on the study.

“The amounts of fat stored in the liver and circulating in the blood were consistently lower for the test group of participants when they consumed complex carbohydrate instead of fructose.”
The research was published in The Journal of Clinical Endocrinology & Metabolism and noted on


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