Wellmune WGP reduced allergy symptoms, clinical study

Wellmune WGP reduced allergy symptoms, clinical study

Wellmune WGP, a natural immune health ingredient for foods, beverages and supplements, reduced seasonal allergy symptoms and improved the quality of life of ragweed allergy sufferers according to clinical results published in the peer-reviewed journal Food Science & Nutrition.


An estimated 40 to 50 million Americans are affected by allergies, with ragweed a leading cause of seasonal allergy symptoms including nasal congestion, sneezing, itchy eyes and difficulty breathing. Allergy symptoms are caused by an immune system overreaction to ragweed pollen.

The placebo-controlled, double-blinded study of 48 healthy people who were subjected to high pollencounts demonstrated statistically significant (p<0.05):


·      Reductions in overall symptoms and severity


·      Reductions in key nasal and eye-related allergy symptoms


·      Improvement on the Quality of Life Index, a scientifically validated tool for measuring how participants rate their overall sense of wellness.

Wellmune, a proprietary baker’s yeast beta glucan, mobilizes billions of innate immune cells that are part of the body’s natural defenses without over-stimulating the immune system. In this study, Wellmune was found to modulate the immune system when less of an immune response was needed.

The results of this study are consistent with numerous previous peer-reviewed, published studies demonstrating that Wellmune can safely prime the immune system to keep the body healthy.

“The findings suggest that Wellmune WGP can play an effective role in reducing seasonal allergy symptoms among ragweed allergy sufferers,” said Shawn M. Talbott, Ph.D., lead investigator, GLH Nutrition, LLC. “While these results are encouraging, additional studies including more study participants should be conducted.”

“A daily regimen including all-natural Wellmune WGP is well-documented to safely support immune health, a key contributor to overall health and well-being,” said Richard Mueller, chief executive officer, Biothera. “Given the important role immune modulation plays in managing symptoms, allergy sufferers who choose foods, beverages and supplements with clinically proven immune support can help ease their discomfort during allergy season.”

Study Design

The randomized, placebo-controlled, double-blind study included self-described “moderate” ragweed allergy sufferers. Forty-eight healthy subjects were equally divided 48 healthy subjects (31 female, 17 male; 39± 13 years of age) into two groups. One group consumed a placebo while the other a 250 mg serving of Wellmune WGP daily for four weeks during September/October 2011 in an area of southeast Ohio with high pollen counts. Participants completed allergy surveys including the validated Rhinoconjunctivitis Quality of Life Questionnaire (RQLQ) to assess differences in allergy symptoms.  Abstract available.

The research was funded by Biothera, Inc.

About Wellmune WGP®

Wellmune WGP is a natural yeast beta 1,3/1,6 glucan that is clinically proven to prime key immune cells that keep the body healthy. This unique food, beverage and supplement ingredient has regulatory approval around the world, including GRAS status in the U.S. and novel foods approval in Europe and China.  It is also patented, Kosher, Halal, non-allergenic and GMO-free. In addition to receiving an IFT Innovation Award, Wellmune has received a SupplySide West ScientificExcellence Award and a Frost & Sullivan Excellence in Research Award. Wellmune WGP is a product of Biothera, a U.S. biotechnology company dedicated to improving immune health.

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