Wacker premieres nature-identical hydroxytyrosol

Wacker premieres nature-identical hydroxytyrosol

Company debuts HTEssence for supplement, functional beverage and cosmetic formulations and also showcases its highly bioavailable cyclodextrin-curcumin formulation.

At SupplySide West 2014, WACKER is premiering its nature-identical hydroxytyrosol for applications in the food and cosmetic industries. Hydroxytyrosol is a highly effective antioxidant that is claimed to have therapeutic effects on joints, the immune system, cardiovascular health and more. Acting as a free-radical scavenger, hydroxytyrosol can also reduce the appearance of skin aging and dark pigmentation. With WACKER’s new patented process, it is now possible to synthesize a nature-identical substance of much greater purity, free of unwanted byproducts, and with a defined amount of active ingredient. WACKER’s HTEssence® offers an excellent price-to-performance ratio and is easy to process in dietary supplements, functional beverages and cosmetics. At the same time, WACKER is presenting a highly bioavailable cyclodextrin-curcumin formulation, which demonstrably increases curcumin’s bioavailability by a factor of 47 compared with conventional curcumin extract. SupplySide West 2014 takes place in Las Vegas Oct. 6 to 10.

WACKER’s nature-identical hydroxytyrosol is a very effective, high-purity antioxidant, free of unwanted byproducts and with a defined amount of active ingredient. Its HTEssence is easy to process in dietary supplements, functional beverages and cosmetics.

Hydroxytyrosol, a secondary plant metabolite, is considered a highly effective antioxidant. Reportedly, it strengthens the immune system, supports normal blood pressure and improves bone and joint health. Above all, it is said to protect blood lipids from oxidative damage. Additionally, hydroxytyrosol is a free-radical scavenger, with an ORAC value (oxygen radical absorbance capacity) of 4,500,000 µmolTE1 per 100 gram—10 times higher than green tea and more than twice as high as coenzyme Q10. In human cells, hydroxytyrosol influences the melanin pigments and can improve the appearance of skin.

Due to its diverse modes of action, hydroxytyrosol is a popular ingredient in dietary supplements and cosmetics. One drawback, until recently, was the way it was produced. In nature, hydroxytyrosol is found in olives and olive leaves and its extraction is complex and cost-intensive. But now, WACKER has developed a novel process to fully synthesize this compound. Its new product, HTEssence, features markedly higher purity with a defined amount of active ingredient.

The controlled production process not only offers supply security, but also ensures that HTEssence does not contain any unwanted byproducts or contaminants. As a result, HTEssence is free of allergens and pesticides. Available as an odorless, water-soluble powder and liquid, the product is suitable for use not only in functional foods and dietary supplements, such as tablets, capsules, energy bars and functional beverages, but also in cosmetics and anti-aging products.

Highly bioavailable curcumin
Curcumin, the active compound in turmeric, is a powerful antioxidant. Because curcumin is extremely hydrophobic, however, it is not readily absorbed in the human bloodstream. This is where cyclodextrins come in. These cyclic starch molecules are hydrophilic on the outside with a hydrophobic cavity on the inside, which allows them to accommodate other hydrophobic substances. Fat-soluble curcumin slips inside the cyclodextrin. In an aqueous medium, the formulation forms a molecular dispersion that is much more readily absorbed by the body.

This effect has been proven scientifically. In a clinical trial, researchers compared the relative absorption of CAVAMAX® W8 Curcumin with pure curcumin extract (95%) and two commercially available curcumin preparations designed to increase bioavailability. The cyclodextrin-curcumin formulation was absorbed up to 47 times more efficiently than the standard extract, and at least 4.5 times better than the next best comparable commercial product. The use of cyclodextrins demonstrably improves the bioavailability of hydrophobic ingredients such as curcumin.

As free-flowing powders, cyclodextrin-based formulations are suitable not only for dry or powdered food supplements, such as tablets, capsules and energy bars, but also for functional beverages.

Visit WACKER at SupplySide West 2014: Booth 16054.

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