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Hyaluronic Acid Binding Peptides Prevent Experimental Staphylococcal Wound Infection

Research presented in Antimicrobial Agents And Chemotherapy (Nov. 2006, p. 3856–3860) entitled “Hyaluronic Acid Binding Peptides Prevent Experimental Staphylococcal Wound Infection” showed that the wound infections caused by Staphylococcus aureus could be prevented by Hyaluronic acid binding peptides.

"Hyaluronic acid binding peptides have been shown to modulate cellular trafficking during host responses and were assessed for their ability to treat and possibly prevent experimental surgical wound infections caused by S. aureus. Treatment with these peptides was highly efficacious in reducing the number of S. aureus cells at the wound site and ameliorated the inflammatory host response associated with these infections. These data suggest a novel approach for the treatment and prophylaxis of staphylococcal wound infections in the clinical setting."

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