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Bioriginal relaunches website

Bioriginal relaunches website

This year marks our 20th year of omega innovation, and to celebrate this milestone, along with many other exciting changes coming up, we’re pleased to announce the launch of our newly redesigned website, The new site offers our customers a fresh clean look, user-friendly navigation and all new content.

Developed with our customers in mind, our new website provides resources, scientific articles, product information and industry news. The site also offers further insight into who Bioriginal is, why we’re passionate about what we do and most importantly to us, how we can help you, our customers. You’ll find information and resources on our diverse capabilities, omega expertise and proprietary processes that we use to develop and deliver innovative custom omega solutions to help you differentiate and compete in our increasingly competitive space.

We’ve made it easy to get in touch with us for any information or help you need, with quick contact forms on each page. You can also follow us on our LinkedIn page to stay up to date with our news and events, and connect with our team to get any additional support you need.

The website will be updated regularly with new features, articles and the latest industry and Bioriginal news. To receive the latest news and information, delivered right to your inbox, you can also sign up for our new omega newsletter, with our first issue launching at the end of May.


Wonderful Brands buys Cuties trademark

Wonderful Brands buys Cuties trademark

Paramount Citrus, America's largest citrus grower, announced the acquisition of the Cuties trademark by Sun Pacific as part of a strategic move by Paramount and Wonderful Brands to oversee all facets of the production, sale and marketing for most of the country's California mandarin crop.

Paramount Citrus will partner with Fowler Packing, a significant and well-known mandarin grower and processor based in Fresno. Together, the two companies will grow, process, market and sell more than 60 percent of the country's California mandarin crop.

Paramount Citrus will make a substantial, multiyear marketing and advertising investment to build a stronger brand for mandarins under the "Wonderful" label. California mandarins sold by Paramount Citrus will be available in stores under a new name this November.

"It's important for us to control our own destiny and oversee all production, marketing and sales, so we can guarantee our customers the unsurpassed taste and quality they've grown to expect," said Paramount Citrus President David Krause. "We'll continue to lead the market as we grow, process and sell this uniquely delicious fruit."

Paramount Citrus will end its joint venture with the commodity grower Sun Pacific this summer. With 14,000 acres of mandarin orchards located primarily in California's San Joaquin Valley, Paramount Citrus will remain the industry's largest grower of the sweet, seedless fruit.

Wonderful Brands is currently the fastest-growing brand in America's produce aisles. Its portfolio includes POM Wonderful, Wonderful Pistachios, Wonderful Almonds, and Wonderful Almond Accents. In addition to California mandarins, Paramount Citrus also will begin selling sweet Texas red grapefruit under the Wonderful label this fall.

Both Paramount Citrus and Wonderful Brands are part of the Roll Global family of companies.

"No one builds consumer brands better than Roll Global," Krause said. "Pomegranates and pistachios were seasonal commodities before our parent company's marketing and sales expertise transformed POM Wonderful and Wonderful Pistachios into category leaders and household names. There are exciting times ahead for customers and consumers of our Wonderful mandarins."

What's new in the world of sweeteners

What's new in the world of sweeteners

In the past two years, major changes have hit the sweeteners marketplace.

If you're just waking up from a long winter's nap, here are a few highlights you should know:

1. Organic erythritol is back on the market.

A polyol (sugar alcohol) found in low levels in fruits and fermented foods, erythritol often serves as a zero-calorie sucrose replacer in foods.

Cargill began offering an organic version in 2009, but then abruptly pulled the product when it decided it wasn't making enough money. The decision highlighted how vulnerable many product manufacturers are to their organic ingredient suppliers.

"There was a lot of heartburn about that one," said Tim Avila, owner of Zsweet erithritol ingredient. "There were some very successful finished products, like Organic Zero, which was straight erythritol in a bag, that suddenly had the carpet pulled out from under them."

A Chinese company has stepped forward to fill the vacuum. The new supplier came too late for Wholesome Sweeteners, however. The company no longer carries Organic Zero, and instead has relaunched its All-Natural Zero and Organic Stevia products.

Other erythritol news in the coming year, Avila predicts, is a "tsunami" of erythritol/stevia blends will be flooding the market. "Several were premiered at Expo West in March, and there are lots of people in the wings who are going to do it too," he said.

2. Consumers are continuing to turn to lower-calorie beverages.

In terms of servings, lower-calorie beverages gained 9.5 percent between 2006 and 2011. In terms of share of total sales, lower-calorie drinks claimed 32.4 percent of sales in 2006, versus 34.1 percent of sales in 2011.

3. New natural sweetening compounds in the works. 

In October 2012, San-Diego-based flavor innovator Senomyx announced it is screening a series of novel plant-based high-potency natural sweetening compounds in a bid to find the next stevia or monk fruit—and in fact a compound had been identified.

The company secured GRAS status for its sucrose enhancer S9632. Senomyx has cash reserves of almost $50 million and is expecting to post net losses of $8 to 10 million on revenues of $30-$33 million in fiscal 2012.

Want to learn more? This is a small part of the Engredea Monograph: Sweeteners Edition. Click here, for more information!


AHPA presents 'Best Practices for Change Control' teleseminar

AHPA presents 'Best Practices for Change Control' teleseminar

The American Herbal Products Association (AHPA) presents a two-hour educational teleseminar titled "Best Practices for Change Control" on June 20, from 1 to 3 p.m. EDT.

The teleseminar, part of the cGMP Compliance Series, will provide information about the process of implementing changes to current good manufacturing practice (cGMP)-related operations and other business systems in a manner that ensures effectiveness and continued compliance with federal regulations covering dietary supplements.

Change control can be applied to any business system, but in a cGMP context it can be applied to:

  • Products (formulas, labels, etc.)
  • Processes (manufacturing processes, test methods, etc.)
  • Equipment and facilities (rooms, utility systems, process equipment, test equipment, instruments, utensils)
  • Components and supplies, and vendors thereof
  • Software, spreadsheets
  • Personnel
  • Documents (standard operating procedures (SOPs), master manufacturing records, specification documents, forms, logs, etc.)

"Some changes can be routine and can be controlled by establishing SOPs," said AHPA Chief Operations Officer Devon Powell. "This teleseminar is designed to address more substantial changes, such as installing new manufacturing equipment or significantly changing a manufacturing process, which may need to be evaluated on a case-by-case basis."

Registration is available through June 19 at a cost of $195 for AHPA members and $495 for non-AHPA members. Registration includes one audio connection and a certificate of attendance for training files. Audio recordings and additional attendee certificates will also be available for purchase. For more information and to register, visit the AHPA website.

Other educational seminar proceedings from the AHPA cGMP Compliance Series are available for purchase from the association's online bookstore.


Vitamin C no help for gout

Vitamin C no help for gout

Despite previous studies touting its benefit in moderating gout risk, new research reveals that vitamin C, also known ascorbic acid, does not reduce uric acid (urate) levels to a clinically significant degree in patients with established gout. Vitamin C supplementation, alone or in combination with allopurinol, appears to have a weak effect on lowering uric acid levels in gout patients according to the results published in the American College of Rheumatology (ACR) journal Arthritis & Rheumatism.

Gout is an inflammatory arthritis that causes excruciating pain and swelling triggered by the crystallization of uric acid within the joints. Estimates from the ACR report that more than 8.3 million Americans suffer with gout. Medical evidence reports that long-term gout management requires treatment with medications that lower urate levels by inhibiting uric acid production (allopurinol) or increasing uric acid excretion (probenecid) through the kidneys.

“While current treatments are successful in reducing the amount of uric acid in the blood, there are many patients who fail to reach appropriate urate levels and need additional therapies,” explains lead author, Prof. Lisa Stamp, from the University of Otago in Christchurch, New Zealand. “Vitamin supplementation is one such alternative therapy and the focus of our current study, which looked at the effects of vitamin C on urate levels in patients with gout.”

The team recruited gout patients who had urate levels greater than the ACR treatment target level of 0.36 mmol/L (6 mg/100 mL). Of the 40 participants with gout, 20 patients already taking allopurinol were given an additional 500 mg dose of vitamin C daily or had the dose of allopurinol increased, while another 20 patients not already taking allopurinol were either started on allopurinol or vitamin C (500 mg/day). Researchers analyzed blood levels of vitamin C (ascorbate), creatinine and uric acid at baseline and week eight.

Study findings show that a modest vitamin C dose for eight weeks did not lower urate levels to a clinically significant degree in gout patients, but did increase ascorbate. The results differ from previous research which found that vitamin C reduced urate levels in healthy individuals without gout, but with high levels of uric acid (hyperuricemia). In fact, the Stamp et al. study found that reduction of uric acid was significantly less in gout patients taking vitamin C compared to those who started or increased their dose of allopurinol.

“Though vitamin C may reduce risk of developing gout, our data does not support using vitamin C as a therapy to lower uric acid levels in patients with established gout,” concludes Prof. Stamp. “Further investigation of the urate lowering effects of a larger vitamin C dose in those with gout is warranted.”


Pistachios: all the polyphenols, not all the fat

Pistachios: all the polyphenols, not all the fat

A new research study, using an experimental model that mimics digestion, suggests that nearly all of the polyphenols in pistachios are released to the body during digestion. The new findings, when considered along with earlier research that suggests dietary fat may not be completely absorbed, is a win-win for those on the lookout for nutrient-rich snacks they can feel good about as part of an overall healthy diet.

The new study appears in the January issue of the Journal of Nutrition and was conducted by the Model Gut Group at the Institute of Food Research (IFR) in the United Kingdom in association with the University of Messina, Italy.

The study specifically looked at polyphenols and antioxidants, such as gamma-tocopherol (vitamin E), found in pistachios. The study found that these polyphenols and antioxidants, which are also found in fruits and vegetables, are released during digestion, making them available to the body.

This study may be interesting because it suggests that the body may be able to absorb the polyphenols and antioxidants found in pistachios, which may be significant because nutrients aren't always readily accessible by the body. As an example, iron in spinach is naturally harder for the human body to absorb. However, the iron can be made more readily absorbed by the body when combined with vitamin C.

Pistachios: antioxidants you can see
Pistachios are the colorful nut, owing their green, yellow, and purple-red colors to the antioxidants and polyphenols found in the kernels and skins. It's easy to spot the good nutrition provided by pistachios: their true colors shine through in their green and yellow kernels, and their purple and red skins.

Fat in pistachios may not be completely absorbed
A preliminary study published in the January 2012 issue of British Journal of Nutrition suggests that the fat in pistachios may not be completely absorbed by the body. The small, randomized controlled‐feeding study, which is the first‐of‐its‐kind research with nuts, suggests we may consume less calories per serving than originally thought. Conducted by the Agricultural Research Service (ARS) of the United States Department of Agriculture (USDA), the study suggests that pistachios provide 160 calories per 30 gram serving (approximately 1 ounce).

The research measured the energy value of pistachios by feeding 16 healthy adults the nuts as part of a controlled diet and calculating the energy value from differences in energy excretion during the dietary treatment timeframe. The resulting energy value of one 30‐gram serving of pistachios was 5 percent less than previous calculations.

The snacking bottom line
Pistachios are a great-tasting, fun, and healthy snack with protein, fiber, and antioxidants. A naturally cholesterol-free food, 90-percent of the fat in pistachios is the healthy unsaturated type. A one-ounce serving of pistachios equals 49 nuts, which is more nuts per serving than any other snack nut. Be sure to color your plate with pistachios.


Brenda Watson's 'Heart of Perfect Health' returns to PBS

Brenda Watson's 'Heart of Perfect Health' returns to PBS

Brenda Watson, best-selling author, renowned PBS-TV educator and digestive health expert returns to the air the first half of June with her myth-busting, life-changing Public Television special, “Heart of Perfect Health: The Startling Truths about Heart Disease and the Power You Hold to Stop It”—shedding light on the silent inflammation epidemic and what Americans can do to live longer, healthier and more productive lives.

“Heart of Perfect Health” receives tremendous response
Due to its overwhelming success, “Heart of Perfect Health” will be airing again nationwide during the first half of June. This popular Public Television special has already raised more than $1 million since its debut in November of last year.

Transforming America’s health
For the past 20 years, Brenda Watson has committed herself to uncovering the core of optimum health with her in-depth experience with digestive care, digestive disease and its many health repercussions. Her best-selling books, health supplements, PBS shows and clinics have reached millions across America, giving them the tools to transform their health through a powerfully simple and integrated approach.

“Heart of Perfect Health”: the startling truths about heart disease
“Silent inflammation is not often discussed in medical circles, but it is critical to understand that it can be reversed. I especially encourage those with heart disease, high cholesterol, high blood pressure and high blood sugar to watch. This show has proved to be a real eye-opener for millions of viewers. Silent inflammation is so pervasive—and evasive—that most people have no idea it is happening to them,” Watson stated.

And the power you hold to stop it
“Heart of Perfect Health” is not simply about the problem of silent inflammation, but about the real and accessible solutions we all have to stop silent inflammation and improve heart disease health markers—high cholesterol, high blood pressure and high blood sugar.

“We don’t think of the gut when we think of heart disease,” says Watson, “though these two areas of the body are indeed linked. This groundbreaking PBS show details this connection and what we can do to reverse the vicious cycle of silent inflammation for good, and avoid becoming another health statistic. Viewers have been shocked at what is causing their silent inflammation and delighted with the power they hold to turn it around, starting in their own kitchens.”



Nutrition 21 launches Nitrosigine

Nutrition 21 LLC, a leading developer and marketer of nutritional ingredients whose health benefits are substantiated by extensive clinical research, proudly announced the launch of Nitrosigine™, a novel patented source of inositol-stabilized arginine silicate accepted by the United States Food and Drug Administration (FDA) as a New Dietary Ingredient (NDI). In pre-clinical studies, Nitrosigine has been shown to demonstrate superiority over arginine in blood flow markers and has been shown to positively affect silicon absorption, providing evidence of health benefits applicable to many market categories.

"Nitrosigine is an exciting addition to our ingredient division and we anticipate it will allow our customers to impact consumers in the sports nutrition, cardiovascular health and men’s health categories. Nitrosigine also validates our ability to develop patent-protected NDIs,” explained Michael Satow, president and CEO of Nutrition 21.

Primary investigator, Dr. James C. Russell, Professor Emeritus, Department of Surgery, Metabolic and Cardiovascular Diseases Laboratory at the Alberta Institute for Human Nutrition, University of Alberta, Canada and his colleagues conducted one of the preclinical studies, entitled “Metabolic Effects of a Novel Silicate Inositol Complex of the Nitric Oxide Precursor Arginine in the Obese Insulin-resistant JCR:LA-cp Rat.” Their research concluded that the arginine silicate inositol complex is absorbed efficiently; raising plasma arginine levels, and is more biologically effective than arginine hydrochloride. Dr. Russell stated, “Our research has shown significant protective effects of the novel amino acid compound arginine silicate in an animal model of the metabolic syndrome.”

The benefits seen with Nitrosigine in enhancing coronary blood flow can also be applied to other categories, including sports nutrition and men’s health. Arginine has been studied extensively since 1998 as a natural metabolic donor of nitric oxide. There is also accumulated evidence over the past 35 years suggesting an important role for silicon in connective tissue and for bone health. Nitrosigine provides the benefits of arginine and silicon, with additional benefits from the unique combination,” said James Komorowski, MS, CNS, vice president of scientific and regulatory affairs at Nutrition 21.

Nitrosigine science highlights
Research has shown dramatic protective effects of the novel amino acid compound arginine silicate in preclinical studies. Results with human subjects are anticipated for Q3 2013.

  • Nitrosigine almost doubles maximum blood flow compared to Arginine HCI and is four times greater than control
  • Nitrosigine blood vessel relaxation is almost five times greater than Arginine HCI
  • Nitrosigine supplementation significantly increased silicon blood levels compared to normal dietary intake



Acquisition powers Flowers Foods sales spike

Acquisition powers Flowers Foods sales spike

Flowers Foods Inc. (NYSE: FLO), the second-largest producer and marketer of fresh packaged bakery foods in the United States, reported results for its 16-week first quarter ended April 20, 2013. Sales increased 25.9 percent to $1.13 billion. Diluted EPS, excluding certain benefit/costs, was $0.46, up 64.3 percent from last year's first quarter. The company recorded a benefit of $0.37 per diluted share related to a bargain purchase accounting gain on the Sara Lee/California acquisition and acquisition-related costs of $0.02 per diluted share. Including the benefit and costs, diluted EPS was $0.81. Other highlights for the quarter include:

  • Volume increased 19.3 percent, acquisitions contributed 7.7 percent, and net price/mix was unfavorable 1.1 percent, driven by a change in product mix;
  • Gross margin was 48.2 percent, compared to 46.7 percent for the first quarter of fiscal 2012;
  • EBITDA margin, excluding the benefit/costs, was 12.3 percent for the quarter;
  • Operating margin (EBIT), excluding the benefit/costs, was 9.2 percent;
  • Generated $86.8 million in cash flow from operations;
  • In January, announced an agreement to acquire certain Hostess bread assets. The agreement was approved by the bankruptcy court in March and is currently under regulatory review;
  • In February, completed acquisition of the Sara Lee and Earthgrains brands for sliced breads, buns, and rolls in the state of California from BBU, Inc. The new business is being rolled out in stages through early summer;
  • Announced the election by the board of directors of Allen L. Shiver, current president of Flowers Foods, as chief executive officer and George E. Deese, current chairman of the board and chief executive officer, as executive chairman, effective May 22, 2013 at the annual shareholders meeting;
  • In April, entered into a new term loan with a commitment of up to $300.0 million and amended existing $500.0 million senior unsecured credit facility and existing term loan to reflect more favorable terms in anticipation of funding for acquisitions and other needs.

Commenting on first quarter results, Chairman and CEO George Deese said, "We believe the results we reported today reflect the best performance in the company's history. We achieved substantial sales increases in both segments, across all channels, and in our primary product categories. We also delivered outstanding earnings. Throughout our company, team members performed incredibly well as they worked to serve customers' needs following Hostess' departure from the market last fall. Our investments in our bakeries and our distribution systems over several decades, combined with the strength and determination of our team, allowed us to take on new business and meet the needs of existing and new customers.

"This is an exciting time for Flowers Foods as we focus on integrating Lepage Bakeries in the Northeast and Sara Lee in California, while maintaining the gains we have achieved in markets throughout the country in recent months," Deese continued. "Looking ahead, we expect to have growth opportunities in our newer markets as customers and consumers gain confidence in Nature's Own, Tastykake, and our other strong brands."

First quarter 2013 results
For the 16-week first quarter of 2013, sales increased 25.9 percent to $1.13 billion from $898.2 million in last year's first quarter. This increase was attributable to increased volumes of 19.3 percent and contributions from the Lepage Bakeries and Sara Lee/California acquisitions of 7.7 percent, partially offset by unfavorable net price/mix of 1.1 percent. Dollar sales and volume increased across all channels. Increases in soft variety, white bread, buns and rolls, and cake primarily drove volume increases in the branded retail channel. The volume increases in the store brand channel were driven by increases in the white bread, buns and rolls, and cake categories. The non-retail channel volume increases were primarily in the foodservice and vending categories. The unfavorable net price/mix was driven primarily by a mix shift in the cake business.

Net income for the quarter, adjusted for a bargain purchase accounting gain and acquisition-related costs, was $64.9 million, or $0.46 per diluted share compared to $37.9 million or $0.28 per diluted share in the first quarter of fiscal 2012. During the first quarter this year, the company recorded a benefit of $51.3 million, net of tax, or $0.37 per diluted share reflecting a bargain purchase accounting gain related to the Sara Lee/California acquisition. Also during the first quarter, Flowers incurred acquisition-related costs of $2.9 million, net of tax, or $0.02 per diluted share. Including these items, net income was $113.3 million, or $0.81 per diluted share.

Gross margin as a percentage of sales for the quarter was 48.2 percent, up 150 basis points from 46.7 percent in the first quarter of 2012. This increase was due primarily to higher sales volumes and decreased workforce-related costs as a percent of sales.

Selling, distribution, and administrative costs as a percent of sales for the quarter were 36.4 percent, down 40 basis points from 36.8 percent of sales in the first quarter of fiscal 2012. Higher sales volumes and lower workforce-related costs as a percent of sales were the main drivers of the decrease. Acquisition-related costs negatively impacted selling, distribution, and administrative costs by $4.5 million, or 40 basis points as a percent of sales, in the first quarter of this year.

Depreciation and amortization expenses for the quarter remained relatively stable as a percent of sales compared to last year's first quarter. Net interest expense increased in this year's first quarter as compared to last year's first quarter primarily as a result of the issuance of $400.0 million of senior notes late in the first quarter of last year. The effective tax rate for the quarter was 22.8 percent as compared to 35.9 percent in last year's first quarter. The bargain purchase accounting gain on the Sara Lee/California acquisition positively affected the tax rate 12.2 percent during the first quarter. The full-year tax rate is expected to be approximately 35.5 percent to 36.0 percent, excluding the effect of the bargain purchase.

Income from operations defined as earnings before interest and taxes (EBIT) adjusted for the bargain purchase accounting gain and the acquisition-related costs, was $104.4 million, or 9.2 percent of sales compared to $59.2 million, or 6.6 percent of sales in last year's first quarter. Including the benefit/costs, EBIT was $151.2 million, or 13.4 percent of sales. Adjusted for the benefit/costs, earnings before interest, taxes, depreciation, and amortization (EBITDA) for the first quarter was $138.6 million, or 12.3 percent of sales, compared to $89.0 million, or 9.9 percent of sales, in last year's first quarter. Including the benefit/costs, EBITDA was $185.4 million, or 16.4 percent of sales.


GSC Packaging named fastest growing private company

GSC Packaging named fastest growing private company

GSC Packaging, a nationwide provider of turnkey contract packaging solutions, earned the number one spot in the Atlanta Business Chronicle’s 2013 Pacesetter Awards, which recognize Atlanta’s 100 fastest-growing private companies. GSC Packaging is one of the largest contract packagers of powdered foods, drink mixes, supplements and diet products in the United States. GSC Packaging specializes in multiple forms of food contract packaging and secondary packaging solutions, including stick packs, pouches, large format pouches, vertical form fill seal pouches, and horizontal form fill seal pouches, among other popular flexible pouch formats. Between 2010 and 2012, GSC Packaging increased revenue 3,265 percent due to the addition of new clients. The company also grew from 30 employees in 2010 to 300 in 2012.

“Contract packaging is in-demand as food manufacturers are realizing the cost-benefits of expanding production without requiring a capital investment in managing expensive facilities, equipment, and personnel,” said Bob Shapiro, CEO of GSC Packaging. “Contract packagers also offer manufacturers a decreased lead-time to market and built-in expertise in packaging design, quality procedures, and food safety.”

To keep up with the company’s rapid growth, GSC Packaging recently moved to a 100,000-square-foot facility at 575 Wharton Drive in Atlanta. Extensive renovations of the facility have transformed the building into a custom, state-of-the-art food contract packaging facility. The new GSC Packaging facility features fifteen production lines, including seven horizontal form/fill/seal (FFS) lines, three six-lane stick pack packaging lines, as well as various semi-automatic, large format automatic, and secondary packaging and kitting lines. The new packaging facility also features a state-of-the-art layout and design, the latest air-handling technology, lot code tracking, real-time computerized inventory control, dust control and air-conditioned storage. The facility layout was custom designed to isolate products into separate suites that package only one specific product at a time to prevent cross-contamination. For added security, the facility also features cameras in each individual suite. Packaged products travel through small openings in the walls to separate secondary packaging areas, which further protects exposed products. In addition, the Atlanta location provides clients with strategic national distribution capabilities.

To qualify for the Pacesetter Awards, companies have to be privately owned, based in the 20-county metro Atlanta area, and not be a subsidiary of another company. Companies also have to be established before the first quarter of 2010, have a two-year growth in sales of more than 50 percent, and have between $1 million and $300 million in revenue in 2012. Companies are ranked by a growth index formula, used to even the playing field among businesses of various sizes. The revenue and employee growth indexes are the percent change from 2010 through 2012, multiplied by the absolute change for the same years. A company’s average employee or revenue growth index is the growth index divided by the average growth index of all companies that qualify. The weighted average growth index is a company’s average employee index score, plus its average revenue index score. Employee growth is weighted 40 percent and revenue growth is weighted 60 percent.