Cardiovascular Health Review Article Suggests Pycnogenol(R) May Act as 'Polypill'

French maritime pine bark extract may be focus of single pill concept to reduce cardiovascular risk factors

NEW JERSEY -December 18, 2003 - A recently published review article on the antioxidant Pycnogenol® (pic-noj-en-all) and its effect on the cardiovascular system, has concluded the ingredient has the potential to counteract major cardiovascular risk factors. The article, published this month in Evidence-Based Integrative Medicine, provides an overview of clinical studies demonstrating Pycnogenol's® heart health benefits including reducing platelet activity, lowering high blood pressure, relaxing artery constriction and improving circulation.

"I have worked extensively with Pycnogneol® in the last decade, studying and conducting research on this super-strength antioxidant. I find it intriguing that studies carried out by different researchers across the globe have similar results to mine, with support to the concept that Pycnogneol® supplementation - between 25mg and 200mg - helps to combat cardiovascular risk factors and contribute to overall heart health and maintenance, said Ronald R. Watson, Ph.D., College of Public Health and School of Medicine, University of Arizona and author of this review.

According to the article, Pycnogneol® and Cardiovascular Health, British scientists recently submitted a proposal that suggests supplementing individuals 55 years of age and older with a drug combination in the form of a single pill. This original 'polypill' concept could reduce cardiovascular risk factors which include lowering bad (LDL) cholesterol and blood pressure, reducing platelet activity and improving circulation.

"While we find this 'polypill' concept appealing and Pycnogenol® may act as a natural 'polypill', it's important for us to recognize that overall cardiovascular health is attainable through nutritional methods. To date, over ten published clinical studies on Pycnogenol® demonstrate its significant benefit for heart and circulatory health. The majority of the research conducted provides solid evidence that this antioxidant is powerful in reducing inflammation in the body, strengthening the vascular system, lowering high blood pressure and cholesterol and fighting the effects of smoking, stress and other environmental risk factors on the heart, " commented Dr. Watson.

Pycnogenol® is the brand name of a natural plant extract originating from the bark of the Maritime pine that grows along the coast of southwest France and is found to contain a unique combination procyanidins and bioflavonoids, which offer extensive natural health benefits. It has been widely studied for the past thirty-five years and has over 100 published studies and review articles ensuring the ingredients safety and efficacy as an ingredient. For more information or a copy of this review article go to


Natural Health Science Inc., (NHS) based in Hillside, New Jersey, is the North American distributor for Pycnogenol® (pic-noj-en-all) brand French maritime pine bark extract on behalf of Horphag Research. Pycnogenol® is a registered trademark of Horphag Research Ltd., Guernsey, and its applications are protected by U.S. patents #4,698,360 / #5,720,956 / #6,372.266 and other international patents. NHS has the exclusive rights to market and sell Pycnogenol® and benefits from over thirty years of scientific research assuring the safety and efficacy of Pycnogenol® as a dietary supplement. For more information about Pycnogenol® visit our web site at

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