HA (Hyaluronic Acid) is a glycosaminoglycan that occurs naturally throughout human and animal's body. It is a major lubricating component of the joints and acts to help improve joint movement, lubrication and cushioning. Sodium Hyaluronate (SH) is the sodium salt of hyaluronic acid, habitually also called HA.
Fenchem has conducted an animal test—using the company’s Hyamax natural sourced Sodium Hyaluronate, to evaluate the absorption and efficacy of oral HA on joint health. High-molecular weight HA (HyaMax®, 1MDa) labeled with 99mTechnetium (99mTc-HA) or free 99mTechnetium pertechnetate (99mTc) was administered to rats and dogs to confirm an earlier study finding uptake of oral HA, and control for possible loss of label.
This study concludes that:
·HyaMax® is absorbed when taken orally;
·HyaMax® demonstrates a special affinity for joints and skin
·HyaMax® supports a rationale for biological actions in both Joint and Skin Health.
In USA, HA is popular used in pet food targeted for joint health, and consumed more and more yearly. As the pet ages, the natural production of HA in their body are reduced, making mobility more painful as time goes on. HA is an important daily nutrient supplement for pet joint health. Although a few published reports of oral HA use found benefits for connective tissues, there is no evidence in the literature for uptake into tissues after oral administration of high molecular weight HA when this study was started. The findings of animal study support the application of HA in pet food designed for joint health of animals. Based on this study support, Fenchem expect to enlarge market share of HA in North America and Europe.