The results of a randomized, placebo controlled trial published in the November 21 issue of
AIDS, (November 21, 2003, Volume 17, Issue 17) suggest that multiple micronutrient supplementation may enhance the survival of HIV-infected individuals with CD4 cell counts less than 200.
The study was conducted on 481 HIV-infected individuals living in and around Bangkok, Thailand and measured mortality rates. The rate was lower in the micronutrient treated group among those with low CD4 cell counts.
The researchers suggest that the finding may have a public health impact where access to antiretrovirals is poor and suggest that more work needs to be done to better understand the mechanism.
Trial participants received a commercially available micronutrient and vitamin supplement, Immunace(R), Immunace(R), for up to 48 weeks. The product's patent pending formula contains vitamins, A, D, E, C, K and B complex vitamins together with natural carotenoids, amino acids, and minerals including copper, iron, magnesium, manganese, and selenium.