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Polyphenolics announces protection against atherosclerosis at AHA Presentation

Polyphenolics is pleased to announce that an AHA presentation links procyanidins to endothelin inhibition, protection against atherosclerosis Study shows some polyphenol constituents, like those in Polyphenolics' MegaNaturalT Gold may be more than powerful antioxidants

According to new research presented at the November American Heart Association meeting in Chicago by Professor Roger Corder, William Harvey Research Institute, Queen Mary, University of London, some components of grape seeds and grape skins, identified as procyanidins, have been shown to inhibit the synthesis of endothelin-1, a vascular hormone known to play a key role in many of the processes underlying vascular dysfunction and the development of atherosclerosis. The news is significant because it indicates polyphenols may be beneficial for more than their well-researched antioxidant properties.

Dr. Corder, previously examined similar effects of purified procyanidins extracted from red wines. "The exciting news is that these tests were conducted on the commercial grape seed extract produced by Polyphenolics as MegaNaturalT Gold grape seed extract. Our estimates suggest that an effective daily dose would be 400 mg. of this extract."

Polyphenolics is a division of Canandaigua Wine Company and manufactures and markets ingredients for the pharmaceutical, nutritional, and beverage industries. For more information about the benefits of phenols, contact Ron Martin at (574) 243-9825, see your local health food retailer or visit

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