Supply Spotlight: Kyowa Hakko

Baby boomers want renewal, physically and mentally, and Kyowa Hakko is striving to provide the science they're seeking.

The international health ingredients manufacturer recently launched two natural, fermentation-based, animal-free products: Resilen?-200, a low molecular weight hyaluronic acid used as a supplement for healthy skin and joints; and Lumistor? L-Hydroxyproline, an amino acid that improves skin moisture retention and encourages the proliferation of new skin cells. Both may be used orally or topically.

Resilen? functions as a moisturizer and can hold up to 500 times its weight in water, the company reports. Hyaluronic acid fills the space between cells, collagen and elastin fibers, acting as a lubricant. Lumistor? is a primary constituent of skin collagen, connective tissue and bone, and helps stabilize the collagen 3-D structure, according to Kyowa Hakko.

The anti-ageing nutrients are part of Kyowa Hakko's new area of focus, "Beauty from within." A combination of Resilen? and Lumistor? has been tested and shows that topically there is a synergy between the two materials with enhanced reduction of fine lines and wrinkles.

The buzz over these products is on top of the company's 2004 NutrAward for its Cognizin brand citicoline, a memory enhancer.

Two more products will debut in the fall. "It's not just bringing them out," says Karen Todd, Kyowa Hakko's senior marketing director, "it's continued research."

The anti-ageing market stays steady on its upward trend in the US, and there's tremendous potential for growth in markets worldwide, the company believes.

Kyowa Hakko manufactures more than 50 amino acids and related compounds, as well as nucleic acids, bioproducts and chemicals
Anti-ageing attributes of amino acids is a particular area of interest for the company. Amino acids are huge in sports and weight loss nutrition, but amino acids as anti-ageing nutrients hasn't been "fully discussed," Todd says, a registered dietitian. "It's not just a big molecule that supports, but a big molecule that prevents. That was an eye-opener."

It's an expanding role for amino acids and Kyowa Hakko, as well. Studies are ongoing with one under way at McLean Hospital, an affiliate of Harvard Medical School. Todd says she hopes the new research will be ready this fall for the SupplySide West convention, as well as Nutracon and Supply Expo in 2007.

An international presence
Green chemistry is an integral part of Kyowa Hakko's mission statement, with a commitment to tread lightly on the environment and be responsible in its key marketplaces.

The ecofriendly market is built-in, especially with an industry trend of consumers who demand nonanimal-derived ingredients. "That's a big benefit for us," Todd says.

Hakko in Japanese means fermentation, reflecting the company's key technology. Kyowa Hakko's proprietary fermentation process eliminates any risk of bovine spongiform encephalopathy or transmissible spongiform encephalopathy contamination.

Kyowa Hakko is a raw materials supplier as well as a bio-innovator, with headquarters in Tokyo, and offices in New York and California. The company operates in more than 80 countries and has 50 facilities.

Kyowa Hakko
+1 212 319 5353
Kyowa Hakko manufactures products for use in dietary supplements and the food, cosmetics and pharmaceutical industries. Kyowa Hakko manufactures and formulates more than 50 amino acids and related compounds, as well as nucleic acids, bioproducts and fine chemicals.

The company has invested more than $230 million in research and development, employs more than 1,400 researchers, and holds nearly 2,500 patents. Kyowa Hakko is a Food and Drug Administration-inspected manufacturer and most of its products are certified kosher.

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