Highly stressed hospital workers in Japan reported improved psychological well-being after taking Wellmune WGPR for two weeks, according to a new peer-reviewed study published in Biotherapy, the official journal of the Japan Society for Biological Therapy.

The research, which was conducted at a hospital specializing in dialysis, found that staff members taking one 125 mg capsule of Wellmune WGP daily for 30 days reported improved vigor and reduced depression, anger and fatigue. The results were statistically significant (p<0.05).

"The results are consistent with the data of five clinical studies Biothera has conducted with Wellmune WGP in the U.S.," said Richard Mueller, president of Biothera's Healthcare Group. "The body of research supporting Wellmune WGP demonstrates that this unique ingredient naturally enhances the immune system to protect against potentially harmful effects of physical and psychological stress."

In previous clinical studies involving marathoners, firefighters and individuals with stressful lifestyles, Wellmune WGP reduced the incidence of upper respiratory tract infection symptoms and improved psychological well-being. Like previous studies, researchers in Japan used a Profile of Mood States (POMS) psychological survey to assess changed in mental and physical energy levels and sense of overall well-being.

The study was conducted by Dr. Tsunesuke Kajimoto and Mayu Nozaki of Nippon Biothera Co., Ltd. and Hiroaki Sugisaki of the Fuchu Renal Disease Clinic Shinshikai Medical Corporation.

The citation for the research paper is: Influence of Continuous Intake of Glucopolysaccharide (GPS) Derived from Baker's Yeast on Mood and EmotionalStates <http://www.wellmune.com/Biotherapyabstract5-2010.html> . Biotherapy (2010) 24 (3):255-259. The paper's abstract is available at:
http://www.wellmune.com/Biotherapyabstract5-2010.html

About Wellmune WGPR

Wellmune WGP is a natural ingredient that is clinically proven to enhance key immune cells that are the body's first line of defense. Designed for functional foods, beverages and supplements, Wellmune WGP strengthens innate immune cells to more quickly find and kill foreign challenges. Wellmune WGP also enhances the immune system to protect against the harmful effects of physical or lifestyle stress. Wellmune WGP is patented, GRAS, TGA-approved, Kosher, Halal, non-allergenic and GMO-free. The ingredient is recipient of an IFT Innovation Award and a Frost & Sullivan Excellence in Research Award. Wellmune WGP is a product of Biothera, a U.S. biotechnology company dedicated to improving immune health. More information is available at www.wellmune.com.