Nitrosigine affirmed GRAS

Nutrition 21 LLC announced that the company’s newest sports nutrition product, Nitrosigine® bonded arginine silicate, is now GRAS (Generally Recognized as Safe) affirmed at the level of 1,500 mg per day for use in nutritional bars and beverages. An independent panel of experts approved this level of Nitrosigine as GRAS after careful review of an extensive dossier of safety data that was compiled by Intertek, a preeminent science and regulatory consultant group.

“This newly affirmed GRAS status now enables functional beverage and nutritional bar manufacturers to utilize Nitrosigine and all of its clinically supported claims,” stated Bill Levi, vice president, strategy and business development at Nutrition 21. “Nitrosigine is the perfect ingredient to formulate into sports nutrition products to help enhance performance through an entire workout. Fitness-focused consumers who want to get the most out of their training regimen, will appreciate that Nitrosigineis quickly absorbed by the body, taking effect in 30 minutes and lasting up to three hours.”

Nitrosigine has been clinically shown to significantly boost nitric oxide (NO) levels, a key factor in increasing blood flow to working muscles.  Nitrosigine has also been shown in clinical and preclinical studies to significantly raise arginine and silicon levels—both important nutrients for cardiovascular performance. “The benefits seen with Nitrosigine can also be applied to other categories, including cardiovascular health and men’s health,” said James Komorowski, MS, CNS, vice president scientific and regulatory affairs at Nutrition 21. “Nitrosigine provides the benefits of arginine and silicon, with additional benefits from the unique combination.”

“Consumer demand continues to rise for truly functional food and beverage products,” Levi stated. “However, food companies have indicated that their product development options are limited by the scarcity of functional ingredients that are GRAS at levels supported by clinical study outcomes. Nitrosigine, with its GRAS affirmation at clinically meaningful doses and substantiated health benefits, is perfectly suited to address both consumer and food industry needs.”