For the first time, a study has reported that concentrations of MSM (methylsulfonylmethane) reliably increase in human serum levels when chronically treated with MSM. The study, titled “Serum MSM Concentrations Following One Month of MSM Treatment in Healthy Men,” has just been published in Clinical Pharmacology & Biopharmaceutics and can be viewed online here.
Authored by Richard J. Bloomer and Daniel A. Melcher, both with the University of Memphis’ Department of Health and Sport Sciences, and Rodney L. Benjamin, director of research and development for Bergstrom Nutrition, the randomized, double-blind, placebo-controlled study set out to discover how MSM concentrates within human serum.
“While MSM has been known to have excellent bioavailability, published data within the public domain regarding serum concentrations following chronic ingestion is minimal,” said Benjamin. “The publication of this study may help other researchers by reporting values as measured by NMR and demonstrating how daily MSM supplementation impacts human serum concentrations over the course of a four week period.”
“We found the increase of MSM in serum appeared to be somewhat time-dependent, with the majority of subjects experiencing a continued rise from week two to week four,” said Bloomer. “This provides a starting point for potential future studies related to dosage and time-ranging.”
As the popularity of formulating with MSM continues to grow, the information related to ideal dosing conditions is invaluable to manufacturers and researchers alike. Bergstrom Nutrition’s OptiMSM® has been included in products targeted for the following categories: joint health, exercise recovery, nutricosmetic, beauty from within, and healthy aging.