In an industry first, Fruit d'Or Nutraceuticals and Complete Phytochemical Solutions have worked together to reveal the presence of insoluble proanthocyanidins (PAC) in natural whole organic cranberry powder.
"Through diligence and months of hard work we were able to quantify insoluble PAC in cranberry materials that were previously thought to be devoid of this class of compounds," says Christian G. Krueger, research scientist and CEO of Complete Phytochemical Solutions, LLC. (CPS) "PAC are divided into two categories; soluble (extractable) and insoluble (non-extractable). The soluble PAC are released when a cranberry undergoes a juicing or extraction process. The insoluble PAC are bound to fruit cell wall components such as fiber and remain as insoluble material after the extraction process. Our past experiences in characterizing forages and grains that contained insoluble PAC informed us that these same compounds would also be present in cranberry."
Krueger explains that his team previously developed a cranberry proanthocyanidin (c-PAC) standard that they are currently using as a calibration to quantify soluble PAC. “We used this same c-PAC standard in our analysis of the insoluble PAC, allowing us for the first time to quantify the amount of PAC bound to plant cell wall material. Taking this new approach we found significant amounts of insoluble PAC in both Fruit d’Or’s natural whole organic cranberry powder and organic cranberry protein powder," he reports. "This gave us a new way of looking at cranberry material that was previously thought of as inert."
The testing method conceived by CPS is based on colorimetric assay, and Krueger notes that the company intends to publish the methodology in a peer-reviewed scientific journal. "This is a methodology that will have enormous impact on evaluating the health-promoting ingredients derived from an assortment of fruits and berries—anything that contains PAC," he comments.
Stephen Lukawski, director of sales and marketing for Fruit d'Or Nutraceuticals, the world’s largest organic grower and processor of cranberry and which is first to have its cranberry material quantified for insoluble proanthocyanidins using this methodology, asserts, "CPS' unique methodology is an authentic breakthrough for the industry. Prior methods such as the DMAC method for quantifying soluble PAC cannot be used to quantify insoluble PAC. This new method allows for the first time to be able to measure insoluble PAC. Based on this methodology we can now standardize both soluble and insoluble PAC, which is a game changer for the industry. Research continues to illuminate the powerful health-promoting abilities of cranberry PAC in an extraordinary range of health applications—urinary tract health, oral health, gut health and more, which will accelerate consumer demand for cranberry supplements and functional foods and beverages. We will be ready to work with our brand partners to fulfill that demand with superior quality material thanks to this methodology."
Lukawski adds that based on this discovery, we now know the total amount of PAC being delivered to the gut. This will allow the industry to design studies correlating gut health to urinary tract health. Fruit d'Or "has now established itself as having the highest levels of PAC in its cranberries than other natural cranberry powders. The fact that we are the first to be able to fingerprint our starting cranberry material, we will able to obtain desirable repeatable results in clinical outcome studies. In addition, we are also the first to be able to standardize natural cranberry powder to show insoluble and soluble PAC, which should create a bevy of exciting new product applications. Due to lack of standardization amongst cranberry products this methodology is needed in the cranberry industry to educate consumers. Companies can now reformulate their cranberry products with a better understanding of what to look for when purchasing cranberry powders. This opens doors for a better understanding of all natural cranberry powders versus cranberry extracts.”
Fruit d'Or is a non-GMO nutraceutical cranberry ingredient manufacturer and supplier that controls the source of cranberry from field to harvest to retail. "We bring efficacy, purity, potency and safety to our customers and to their consumers," Lukawski comments.