Lonza Announces New Dietary Supplement Ingredient PepZin GI™

Basel, Switzerland and Fair Lawn, NJ, (September 18, 2002) – Lonza, Inc., announced that the US Food and Drug Administration has allowed the sale of PepZin GI™, the subject of a new dietary ingredient submission to the federal agency. PepZin GI™ is a patented zinc-carnosine complex supported by abundant human and animal data.

Lonza has an exclusive distribution agreement with Hamari Chemicals Ltd. (Osaka, Japan), to market the ingredient in North America and Europe. PepZin GI™ has been used in Japan for over a decade as an ulcer-healing drug under the generic name Polaprezinc (INN). Hamari Chemicals manufactures and holds the patents on this unique compound. PepZin GI™ offers exceptional, “drug-like” patent protection, in that the molecule itself is claimed. This provides Lonza’s strategic marketing partners exceptional exclusivity.

PepZin GI™ is a coordination complex of zinc with the dipeptide L-carnosine. “PepZin GI™ is a unique molecular entity, with biological activity different than that of zinc mixed with carnosine,” offered Anthony L. Almada, MSc, President and Chief Scientific Officer of IMAGINutrition. He added, “We believe PepZin GI™’s data and intellectual property package will usher in a new category of evidence-based dietary supplements.”

Lonza Group is a Life Sciences driven chemical company headquartered in Switzerland, with sales of CHF 2.5 billion in 2001 and operating 21 production and R&D facilities in 9 countries. It employs 6200 people worldwide and is the leading supplier of active chemical ingredients, intermediates and biotechnology solutions to the pharmaceutical and agrochemical industries. It also offers a broad catalogue of organic intermediates for a wide range of applications such as pharmaceuticals, agrochemicals, vitamins, food and feedstuff, dyes and pigments, adhesives and fragrances. Furthermore the Group manufactures specialty biocides and oleochemicals and develops and produces specific polymer intermediates, unsaturated polyester-resins, compounds and composites. For more information on Lonza Group please visit the company’s website at www.lonzagroup.com.

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