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New Study Shows Seditol(TM) Highly Effective For Improving Sleep and Reducing Fatigue

(Irvine, CA)– A new human study conducted by an independent contract research organization has clearly demonstrated that the natural ingredient Seditol™ is highly effective for ensuring a sound night’s sleep and allowing adults to wake up feeling refreshed. The study of forty-five adults, the second such study for Next Pharmaceuticals, reported the percentages of subjects that agreed with the following statements:
Helps ensure a sound night’s sleep: 91%
Allows you to wake up feeling refreshed: 89%
Reduces fatigue due to lack of sleep: 91%
Is gentle to your stomach: 96%
Has less side effects than other sleep aids: 87%
Gives me more energy during the day: 84%

Eighty-two percent (82%) of the subjects rated the product as “effective” in helping them fall asleep and 87% of the subjects reported that they fell asleep quickly. Eighty percent (80%) rated the product as effective in helping them sleep throughout the night. Eighty-seven percent (87%) of the subjects rated the product as effective in providing a restful sleep. Seventy-six percent (76%) of the subjects stated they felt “refreshed” after waking up and 84% rated the product as effective in relieving mild insomnia/sleeplessness.

Seditol™ is a blend of a patented extract of Magnolia officinalis (U.S. Patent No. US 6,582,735) and a proprietary extract of Ziziphus spinosa. “The exciting results of this study confirm the positive results we obtained from our first study.” says Bob Garrison, President and CEO of Next. “We believe Seditol™ can be highly effective for the 70 million Americans who have difficulty sleeping, because it addresses the primary cause of sleeplessness in otherwise healthy adults: an overactive hypothalamic-pituitary-adrenal axis due to unresolved stress. Plus, the pharmacology behind Seditol™ suggests that it is the natural choice for excessive body weight associated with less than adequate sleep.”

New research has shown a significant relationship with the amount of sleep a person gets and their weight/body mass index. A 2005 published paper showed that reduced amounts of sleep are associated with overweight and obese status. (Arch Intern Med, 2005;165:25-30) An explanation for these findings was published in two 2004 studies that demonstrated when people don’t get eight hours of sleep nightly there is an increase in stress hormones at night and an 18% reduction in the hormone leptin that normally helps control appetite, plus a 28% increase in the hormone ghrelin that increases appetite. (Ann Intern Med, 2004 Dec 7;141(11):846-50

Seditol™ is available to manufacturers of dietary supplements as a stand-alone product, or as an ingredient in combination formulas. Next Pharmaceuticals, Inc. is a research and development company that markets its patented or patent-pending ingredients to dietary supplement, food, and beverage companies focused on products for healthy living. For more information on Seditol™ or Next’s other ingredients, visit


Dayna Bird
949.450.0203 ext. 15

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